{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:09:18Z","timestamp":1761948558380,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T00:00:00Z","timestamp":1578182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7182149"],"award-info":[{"award-number":["7182149"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871328"],"award-info":[{"award-number":["81871328"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Quantification of hemodynamics and right ventricular (RV) function is crucial for pulmonary hypertension (PH). Cardiovascular magnetic resonance\u2013based heart deformation analysis (CMR\u2010HDA) has been used to assess the ventricular strain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study was to determine the correlation of right ventricular longitudinal strain (RVLS) assessed with CMR\u2010HDA with RV function as well as hemodynamics in patients with chronic thromboembolic pulmonary hypertension (CTEPH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010six CTEPH patients were prospectively included in this research. Each patients underwent CMR and right heart catheterization (RHC). RVLS and RV ejection fraction (RVEF) was quantified from cine images acquired with a retrospectively gated turbo FLASH gradient\u2010echo sequence. The late gadolinium enhancement (LGE) images were acquired using a 2D inversion recovery phase\u2010sensitive fast gradient\u2010echo sequence. Hemodynamics were determined with RHC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Right ventricular longitudinal strain measured with CMR\u2010HDA was \u221213.99\u00a0\u00b1\u00a04.94%. Bland\u2013Altman plots showed statistical agreement with RVLS with low intra\u2010 and interobserver variability. RVLS correlated with serum N\u2010terminal\u2010pro\u2010B\u2010type natriuretic peptide (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.615, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). RVLS inversely correlated with RVEF (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.699, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), and it was positively correlated with both RVESV (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.664, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) and myocardial the volume of LGE (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.447, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.008). Receiver\u2010operating characteristic (ROC) indicated that RVLS values of &gt;\u221214.20% could be used to predict RVEF &lt;40% with a 100% sensitivity and a 96.7% specificity. Hemodynamically, RVLS was positively correlated with mean pulmonary artery pressure (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.598, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) and pulmonary vascular resistance (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.685, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Right ventricular longitudinal strain assessed by CMR\u2010HDA is a readily available and reproducible parameters of RV function. RVLS &gt;\u221214.20% suggests the presence of RV dysfunction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13128","type":"journal-article","created":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T08:42:17Z","timestamp":1575880937000},"page":"277-284","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["CMR\u2010based heart deformation analysis for quantification of hemodynamics and right ventricular dysfunction in patients with CTEPH"],"prefix":"10.1111","volume":"14","author":[{"given":"Xincao","family":"Tao","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine China\u2010Japan Friendship Hospital Beijing China"},{"name":"Chinese Academy of Medical Sciences Graduate School of Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1298-4441","authenticated-orcid":false,"given":"Min","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanmu","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7096-8792","authenticated-orcid":false,"given":"Zhenguo","family":"Zhai","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine China\u2010Japan Friendship Hospital Beijing China"},{"name":"Chinese Academy of Medical Sciences Graduate School of Peking Union Medical College Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201509-618AS"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.01.042"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl477"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.653576"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4217-6"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25718"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4250\/jcu.2015.23.2.91"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24539"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12111599"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-016-0879-z"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1090-6"},{"issue":"2","key":"e_1_2_10_13_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/oxfordjournals.eurheartj.a059855","article-title":"Doppler echocardiographic evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease. 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