{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:00:25Z","timestamp":1790366425972,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T00:00:00Z","timestamp":1578700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>People with mild chronic obstructive pulmonary disease (COPD) experience exercise intolerance, dyspnoea and poor quality of life. However, the role of pulmonary rehabilitation (PR) in this group is unclear. Objectives: This randomised controlled trial aimed to explore the effects of home\u2010based PR in people with mild COPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>People with mild COPD (FEV<jats:sub>1<\/jats:sub>\/FVC\u00a0&lt;\u00a070%; FEV<jats:sub>1<\/jats:sub>\u00a0&gt;\u00a080%predicted) with a smoking history of \u226510 packet years were randomised to either 8 weeks of home\u2010based PR (one home visit and seven once\u2010weekly telephone calls) or standard care (weekly social telephone calls). Six minute walk distance (6MWD), and Modified Medical Research Council Dyspnoea Scale (mMRC) and Chronic Respiratory Disease Questionnaire (CRQ) scores were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 58 participants (34 males, mean age 68 (SD 9) years, FEV<jats:sub>1<\/jats:sub>%predicted 90 (7), 6MWD 496 (105)\u00a0m) were included with 31 participants randomised to home\u2010based PR. Participants attended an average of 6.8 of the 8 scheduled sessions, ranging from 3 to 8\u00a0sessions. Both groups showed improvements in exercise capacity, symptoms and health\u2010related quality of life (HRQoL) over time, however there was no difference in 6MWD at end\u2010intervention (mean difference \u22123\u00a0m, 95% confidence interval (CI) \u221264 to 58) or 6\u00a0months (7\u00a0m, 95% CI \u221259 to 72). At 6 months home\u2010based PR participants were more likely to have clinically important improvements in CRQ emotional function (50% of home PR vs 0% control, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and CRQ total score (45% vs 17%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For people with mild COPD, home\u2010based PR did not improve exercise capacity more than standard care.<\/jats:p><jats:p>The trial was registered at the Australia New Zealand clinical trial registry (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.anzctr.org.au\">https:\/\/www.anzctr.org.au<\/jats:ext-link>, Trial ID: ACTRN12616000965404).<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13138","type":"journal-article","created":{"date-parts":[[2019,12,27]],"date-time":"2019-12-27T07:20:36Z","timestamp":1577431236000},"page":"335-344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["The impact of home\u2010based pulmonary rehabilitation on people with mild chronic obstructive pulmonary disease: A randomised controlled trial"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2090-0746","authenticated-orcid":false,"given":"Aroub","family":"Lahham","sequence":"first","affiliation":[{"name":"Physiotherapy La Trobe University Melbourne Australia"},{"name":"Institute for Breathing and Sleep Melbourne Australia"},{"name":"Menzies Institute for Medical Research, University of Tasmania Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine F.","family":"McDonald","sequence":"additional","affiliation":[{"name":"Institute for Breathing and Sleep Melbourne Australia"},{"name":"Respiratory and Sleep Medicine, Austin Health Melbourne Australia"},{"name":"Medicine The University of Melbourne Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary","family":"Moore","sequence":"additional","affiliation":[{"name":"Institute for Breathing and Sleep Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narelle S.","family":"Cox","sequence":"additional","affiliation":[{"name":"Physiotherapy La Trobe University Melbourne Australia"},{"name":"Institute for Breathing and Sleep Melbourne Australia"},{"name":"Central Clinical School, Monash University Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Rawlings","sequence":"additional","affiliation":[{"name":"Physiotherapy Monash Health Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Nichols","sequence":"additional","affiliation":[{"name":"Physiotherapy Monash Health Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athina","family":"Liacos","sequence":"additional","affiliation":[{"name":"Physiotherapy La Trobe University Melbourne Australia"},{"name":"Physiotherapy Monash Health Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne E.","family":"Holland","sequence":"additional","affiliation":[{"name":"Physiotherapy La Trobe University Melbourne Australia"},{"name":"Institute for Breathing and Sleep Melbourne Australia"},{"name":"Central Clinical School, Monash University Melbourne Australia"},{"name":"Physiotherapy Alfred Health Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200611-159CC"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2014.09.2808"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201309-1634ST"},{"key":"e_1_2_11_5_1","unstructured":"The Global Strategy for Diagnosis Management and Prevention of COPD.Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017.http:\/\/goldcopd.org. 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