{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:58:59Z","timestamp":1791838739625,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T00:00:00Z","timestamp":1578700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The product (DSP) of the distance walked (meters) and minimum oxygen saturation obtained during the 6\u2010minute walk test (6MWT) has been proposed as a predictor of mortality in idiopathic pulmonary fibrosis and in bronchiectasis not related to cystic fibrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to determine the DSP's ability to predict mortality in patients with chronic obstructive pulmonary disease (COPD) at the outpatient level and compare it to the BODE index and meters walked in the 6MWT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Descriptive observational study in a cohort of patients with COPD being treated at outpatient pulmonology clinics. Each of the patients completed the 6MWT following ATS\/ERS protocols and their BODE index and DSP were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>About 103 patients were included. The average length of follow\u2010up was 36\u00a0months. Patients who died showed a lower number of meters walked in the 6MWT (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), as well as a lower DSP (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). A 6MWT &lt;\u00a0334\u00a0m, a DSP &lt;\u00a0290 and a BODE \u2265\u00a04 showed good prognostic ability at 3\u00a0years (AUC 71%, 69% and 70.4%, respectively). The 6MWT was superior to the BODE index in predicting mortality during the first year of follow\u2010up (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.023). We did not find any differences between DSP and meters walked in the 6MWT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The DSP is a good predictor of mortality, although it does not offer a better prognostic ability than that of meters walked in the 6MWT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13141","type":"journal-article","created":{"date-parts":[[2019,12,28]],"date-time":"2019-12-28T18:45:57Z","timestamp":1577558757000},"page":"364-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Prognostic ability of the distance\u2010saturation product in the 6\u2010minute walk test in patients with chronic obstructive pulmonary disease"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8845-9611","authenticated-orcid":false,"given":"Nikita","family":"Gurbani","sequence":"first","affiliation":[{"name":"Pulmonology and Thoracic Surgery Department Hospital Nuestra Se\u00f1ora de la Candelaria Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1564-1172","authenticated-orcid":false,"given":"Juan Marco","family":"Figueira Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Pulmonology and Thoracic Surgery Department Hospital Nuestra Se\u00f1ora de la Candelaria Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel \u00c1ngel","family":"Garc\u00eda Bello","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics Department Research Unit Hospital Universitario Nuestra Se\u00f1ora de la Candelaria (HUNSC) and Gerencia de Atenci\u00f3n Primaria AP Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Garc\u00eda\u2010Talavera","sequence":"additional","affiliation":[{"name":"Pulmonology and Thoracic Surgery Department Hospital Nuestra Se\u00f1ora de la Candelaria Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Afonso D\u00edaz","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Hospital Nuestra Se\u00f1ora de la Candelaria Santa Cruz de Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021322"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200407-867OC"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61301-5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-002152"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2008.12.005"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200902-0271OC"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4104\/pcrj.2012.00054"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-016-0305-2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00034603"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0520"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2006.06.017"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2006.02.004"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.08.53"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2015.06.013"},{"key":"e_1_2_8_16_1","first-page":"7","article-title":"para la evaluaci\u00f3n del sobrepeso y la obesidad y el establecimiento de criterios de intervenci\u00f3n terap\u00e9utica","volume":"2007","author":"Rubio MA","year":"2007","journal-title":"Rev Esp Obes"},{"key":"e_1_2_8_17_1","unstructured":"Global Strategy for the Diagnosis Management and Prevention of COPD Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017. 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