{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:11:45Z","timestamp":1780449105616,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008376","name":"Helsingin ja Uudenmaan Sairaanhoitopiiri","doi-asserted-by":"publisher","award":["Y code 2019SK003"],"award-info":[{"award-number":["Y code 2019SK003"]}],"id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008376","name":"Helsingin ja Uudenmaan Sairaanhoitopiiri","doi-asserted-by":"publisher","award":["VY1169006"],"award-info":[{"award-number":["VY1169006"]}],"id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Study objectives<\/jats:title><jats:p>We initiated Hypoglossal Neurostimulation therapy (HGNS) at the Helsinki University Hospital in late 2014. Here, we report our experience.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included all 15 HGNS patients. All patients had previously failed both CPAP and oral appliance therapy for sleep apnoea. Overnight polysomnography parameters were analysed before and at 1.5 years with HGNS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean \u00b1 SD patient age was 53 \u00b1 6 years; 2 women and 13 men were included. Mean \u00b1 SD efficient CPAP level was 11.4 \u00b1 3.4 cm H<jats:sub>2<\/jats:sub>O. Implantation technically succeeded in all patients. There were no significant changes of AHI and ODI4 after HGNS [median (quartile) 29.2\/h (19.8\u201038.7) versus 30.1\/h (15.6\u201052.6) and 15.0\/h (5.9\u201020) versus 12.5\/h (6.9\u201030.2) respectively].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We did not observe significant changes in AHI and ODI4 indices with HGNS therapy. Larger multicentre randomised controlled trials are necessary before wider international use of HGNS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13303","type":"journal-article","created":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T10:55:20Z","timestamp":1605264920000},"page":"329-335","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["No changes in nocturnal respiration with hypoglossal neurostimulation therapy for obstructive sleep apnoea"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7367-6613","authenticated-orcid":false,"given":"Adel","family":"Bachour","sequence":"first","affiliation":[{"name":"Sleep Unit, Heart and Lung Center, Helsinki University Hospital University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"B\u00e4ck","sequence":"additional","affiliation":[{"name":"Head and Neck Center, ENT 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