{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:16:41Z","timestamp":1768454201365,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T00:00:00Z","timestamp":1628380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The existing guidelines recommend type III devices should be used in patients without significant comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study explored the reliability of using a type III device in patients with significant medical conditions to diagnose sleep apnea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients had an overnight sleep study conducted simultaneously with both polysomnography (PSG) and a type III (NOX\u2010T3) monitoring device. All patients had stable multiple coexisting medical illnesses without any changes in medications and conditions within 1\u2009month of sleep study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between July 2019 and March 2020, there were altogether 74 patients recruited with analyzable data. Five major disease groups were identified in the cohort: psychiatric illnesses, stroke, ischemic heart diseases (IHDs), chronic kidney diseases (CKDs), and others. Psychiatric patients with medications were found to have the lowest apnea hypopnea index (AHI) (23.7 per hour) and arousal index (46.6 per hour). The CKD group had the highest mean arousal index (71.4 per hour) and obstructive apnea count (110.2). NOX\u2010T3 respiratory event index (REI) was significantly lower than the PSG AHI (mean REI 31.4 vs. mean AHI: 42.2). The number of patients with no\/mild\/moderate\/severe obstructive sleep apnea (OSA) diagnosed by NOX\u2010T3 and PSG was 7\/17\/19\/31 and 5\/11\/20\/38, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>NOX\u2010T3 device can reliably diagnose OSA in patients with different stable coexisting medical conditions. There is a tendency for underestimation of the severity of the OSA with NOX\u2010T3 in patients with coexisting medical conditions especially with sedative medications. A positive NOX\u2010T3 reliably diagnoses OSA whereas a negative NOX\u2010T3 result needs to be interpreted with caution.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13416","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T20:38:02Z","timestamp":1625517482000},"page":"1104-1112","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Using a portable monitoring device for diagnosing obstructive sleep apnea in patients with multiple coexisting medical illnesses"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3829-6700","authenticated-orcid":false,"given":"Kin Wang","family":"To","sequence":"first","affiliation":[{"name":"Respiratory Division, Department of Medicine and Therapeutics, Prince of Wales Hospital The Chinese University of Hong Kong  Hong Kong China"},{"name":"SH Ho Sleep Apnea Management Center The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tat On","family":"Chan","sequence":"additional","affiliation":[{"name":"Respiratory Division, Department of Medicine and Therapeutics, Prince of Wales Hospital The Chinese University of Hong Kong  Hong Kong China"},{"name":"SH Ho Sleep Apnea Management Center The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wing Chi","family":"Chan","sequence":"additional","affiliation":[{"name":"Respiratory Division, Department of Medicine North District Hospital  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kah Lin","family":"Choo","sequence":"additional","affiliation":[{"name":"Respiratory Division, Department of Medicine North District Hospital  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S. 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