{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T13:28:03Z","timestamp":1749648483387,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Inhaled antibiotics reduce the frequency of exacerbations. The objective was to assess the efficacy of inhaled ceftazidime in patients with non\u2010cystic fibrosis bronchiectasis (NCFB) and concomitant chronic bronchial infection (CBI) caused by potentially pathogenic microorganisms (PPM) other than <jats:italic>Pseudomonas aeruginosa<\/jats:italic> (PA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Method<\/jats:title><jats:p>Quasi\u2010experimental study in 21 patients with exacerbations who developed CBI by a PPM other than PA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bacterial infection was resolved in 85.7% patients. Rehospitalizations, length of hospital stay, moderate exacerbations and blood levels of CRP decreased significantly. In addition, SGRQ questionnaire also decreased more than 4 points in 57.1% of the patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results suggest that inhaled ceftazidime in NCFB unrelated to PA is a plausible alternative to the standard therapies used in clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13534","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T09:49:44Z","timestamp":1661507384000},"page":"768-773","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Response to inhaled ceftazidime in patients with non\u2010cystic fibrosis bronchiectasis and chronic bronchial infection unrelated to <i>Pseudomonas aeruginosa<\/i>"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2654-5482","authenticated-orcid":false,"given":"Vanessa","family":"Riveiro","sequence":"first","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Casal","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"\u00c1lvarez\u2010Doba\u00f1o","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"},{"name":"Interdisciplinary Research Group in Pulmonology Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Lourido","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Su\u00e1rez\u2010Artime","sequence":"additional","affiliation":[{"name":"Pharmacy Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlota","family":"Rodr\u00edguez\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc\u00eda","family":"Ferreiro","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"},{"name":"Interdisciplinary Research Group in Pulmonology Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda E.","family":"Toubes","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Vald\u00e9s","sequence":"additional","affiliation":[{"name":"Pulmonology Department University Clinical Hospital of Santiago  Santiago de Compostela Spain"},{"name":"Interdisciplinary Research Group in Pulmonology Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"},{"name":"University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01953\u20102017"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20102600(19)30185\u20107"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201005\u20100756OC"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1569\u20101993(08)60178\u20102"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2017.07.015"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201309\u20101575OC"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S121943"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201711\u20102202OC"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0954\u20106111(99)90090\u20102"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00071312"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.13534","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/crj.13534","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.13534","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T20:52:19Z","timestamp":1692651139000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.13534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,26]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/crj.13534"],"URL":"https:\/\/doi.org\/10.1111\/crj.13534","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"type":"print","value":"1752-6981"},{"type":"electronic","value":"1752-699X"}],"subject":[],"published":{"date-parts":[[2022,8,26]]},"assertion":[{"value":"2022-05-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}