{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:24:36Z","timestamp":1773851076332,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T00:00:00Z","timestamp":1661904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We collected data on ventilator\u2010associated pneumonia (VAP) and hospital\u2010acquired pneumonia (HAP) induced by <jats:italic>Stenotrophomonas maltophilia<\/jats:italic> (SM) and <jats:styled-content style=\"fixed-case\"><jats:italic>Klebsiella pneumoniae<\/jats:italic><\/jats:styled-content> (KP) and compared differences between two bacteria in mortality, duration of ventilator use, length of hospital stay, and risk factors for infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to evaluate the prognosis and to find risk factors of SM\u2010HAP\/VAP versus KP\u2010HAP\/VAP in the intensive care unit (ICU).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study included patients admitted to the ICU between June 2019 and June 2021 and diagnosed with SM\u2010HAP\/VAP or KP\u2010HAP\/VAP. The primary outcome was 28\u2010day mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010two HAP\/VAP patients (48 with SM\u2010HAP\/VAP and 44 with KP\u2010HAP\/VAP) were included. The 28\u2010day mortality was 16.7% (8\/48 patients) in SM\u2010HAP\/VAP and 15.9% (7\/44 patients) in KP\u2010HAP\/VAP (<jats:italic>P<\/jats:italic>\u2009=\u20090.922). After adjustment for potential confounders, the hazard ratios for 28\u2010day mortality in SM\u2010HAP\/VAP were 1.3 (95% CI:0.5\u20133.7), 1.0 (95% CI:0.4\u20133.0), 1.4 (95% CI:0.5\u20134.0), and 1.1 (95% CI:0.4\u20133.4), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SM\u2010HAP\/VAP and KP\u2010HAP\/VAP patients in ICU might have a similar prognosis in mortality, the total duration of the artificial airway and ventilator use, the total length of ICU stay, and hospital stay. The risk factors of SM\u2010HAP\/VAP versus KP\u2010HAP\/VAP might be the artificial airway, ventilator use, gastric tube placement, acid suppressant and antibiotics (especially carbapenem).<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13537","type":"journal-article","created":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T03:34:10Z","timestamp":1662003250000},"page":"669-676","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prognosis of hospital\u2010acquired pneumonia\/ventilator\u2010associated pneumonia with <scp><i>Stenotrophomonas maltophilia<\/i><\/scp> versus <scp><i>Klebsiella pneumoniae<\/i><\/scp> in intensive care unit: A retrospective cohort study"],"prefix":"10.1111","volume":"16","author":[{"given":"Shuping","family":"Chen","sequence":"first","affiliation":[{"name":"Intensive Care Unit Shanghai Jiao Tong University Affiliated Sixth People's Hospital  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3135-9414","authenticated-orcid":false,"given":"Dongdong","family":"Zou","sequence":"additional","affiliation":[{"name":"Neurosurgery Department Shanghai Jiao Tong University Affiliated Sixth People's Hospital  Shanghai 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