{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:06:27Z","timestamp":1781910387289,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The study objective was to estimate the prevalence of chronic hypercapnic respiratory failure (CHRF) and home noninvasive ventilation (NIV) use in a high\u2010risk population, individuals with a history of at least one COPD\u2010related hospitalizations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed electronic medical record data of patients with at least one COPD\u2010related hospitalization between October 1, 2011, and September 30, 2017, to the Iowa City VA Medical Center. We excluded individuals with no obstructive ventilatory defect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 186 patients, the overall prevalence of compensated hypercapnic respiratory failure (CompHRF), defined as PaCO<jats:sub>2<\/jats:sub>\u00a0&gt;\u200945\u2009mmHg with a pH\u2009=\u00a07.35\u20137.45, was 52.7%, while the overall prevalence of home NIV was 4.3%. The prevalence of CompHRF was 43.6% and home NIV was 1.8% in those with one COPD\u2010related hospitalization. Among those with \u22654 COPD\u2010related hospitalizations, the prevalence of CompHRF was 77.8% (14 of 18), and home NIV was 11.1% (2 of 18).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Approximately half of individuals with at least one COPD\u2010related hospitalization have CompHRF, but only 8.2% of those use home NIV. Future studies should estimate CHRF rates and the degree of underutilization of home NIV in larger multicenter samples.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13678","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T05:09:56Z","timestamp":1690866596000},"page":"811-815","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Home noninvasive ventilation use in patients hospitalized with COPD"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-6740","authenticated-orcid":false,"given":"Spyridon","family":"Fortis","sequence":"first","affiliation":[{"name":"Veterans Rural Health Resource Center\u2010Iowa City, VA Office of Rural Health, and Center for Access and Delivery Research and Evaluation (CADRE) at the Iowa City VA Healthcare System  Iowa City Iowa USA"},{"name":"Department of Internal Medicine, Division of Pulmonary, Critical Care, and Occupational Medicine University of Iowa Roy J. and Lucille A. Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Gao","sequence":"additional","affiliation":[{"name":"Veterans Rural Health Resource Center\u2010Iowa City, VA Office of Rural Health, and Center for Access and Delivery Research and Evaluation (CADRE) at the Iowa City VA Healthcare System  Iowa City Iowa USA"},{"name":"Department of Internal Medicine, Division of General Internal Medicine University of Iowa Roy J. and Lucille A. Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelby","family":"Rewerts","sequence":"additional","affiliation":[{"name":"Veterans Rural Health Resource Center\u2010Iowa City, VA Office of Rural Health, and Center for Access and Delivery Research and Evaluation (CADRE) at the Iowa City VA Healthcare System  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Vaughan","family":"Sarrazin","sequence":"additional","affiliation":[{"name":"Veterans Rural Health Resource Center\u2010Iowa City, VA Office of Rural Health, and Center for Access and Delivery Research and Evaluation (CADRE) at the Iowa City VA Healthcare System  Iowa City Iowa USA"},{"name":"Department of Internal Medicine, Division of General Internal Medicine University of Iowa Roy J. and Lucille A. Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Kaboli","sequence":"additional","affiliation":[{"name":"Veterans Rural Health Resource Center\u2010Iowa City, VA Office of Rural Health, and Center for Access and Delivery Research and Evaluation (CADRE) at the Iowa City VA Healthcare System  Iowa City Iowa USA"},{"name":"Department of Internal Medicine, Division of General Internal Medicine University of Iowa Roy J. and Lucille A. Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.4451"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2014.03.006"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20102600(14)70153\u20105"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2016.11.045"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S281162"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.1.9712108"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/09041950.005s1693"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S283020"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202108\u20101912LE"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S222803"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102015\u2010008909"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.05689"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.13678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T08:56:57Z","timestamp":1692694617000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.13678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,31]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1111\/crj.13678"],"URL":"https:\/\/doi.org\/10.1111\/crj.13678","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"value":"1752-6981","type":"print"},{"value":"1752-699X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,31]]},"assertion":[{"value":"2023-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}