{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:26:16Z","timestamp":1753878376991,"version":"3.41.2"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>In this study, we aimed to investigate the prognosis of invasive lung adenocarcinoma that manifests as pure ground glass nodules (pGGNs) and confirm the effectiveness of sublobectomy and lymph node sampling in patients with pGGN\u2010featured invasive adenocarcinoma (IAC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>We retrospectively enrolled 139 patients with pGGN\u2010featured IAC, who underwent complete resection in two medical institutions between January 2011 and May 2022. Stratification analysis was conducted to ensure balanced baseline characteristics among the patients. The 5\u2010year overall survival (OS) and disease\u2010free survival (DFS) rates were compared between the groups using Kaplan\u2013Meier survival curves and log\u2010rank test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 5\u2010year OS and DFS rates for patients with IAC presenting as pGGNs after surgery were 96.5% and 100%, respectively. No lymph node metastasis or recurrence was observed in any of the enrolled patients. There was no statistically significant difference in the 5\u2010year OS between patients who underwent lobectomy or sublobectomy, along with lymph node resection or sampling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>IAC presented as pGGNs exhibited low\u2010grade malignancy and had a relatively good prognosis. Therefore, these patients may be treated with sublobectomy and lymph node sampling.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13766","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T03:14:44Z","timestamp":1715138084000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sublobectomy and lymph node sampling are adequate for patients with invasive lung adenocarcinoma presenting as pure ground glass nodules"],"prefix":"10.1111","volume":"18","author":[{"given":"Hansheng","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery The First Affiliated Hospital of Shantou University Medical College  Shantou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3726-5948","authenticated-orcid":false,"given":"Junhan","family":"Wu","sequence":"additional","affiliation":[{"name":"Shantou University Medical College  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