{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:08:07Z","timestamp":1771060087543,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270099"],"award-info":[{"award-number":["82270099"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) results in a modest reduction in blood pressure. This study aimed to identify parameters from 24\u2010h ambulatory blood pressure monitoring (ABPM) that are predictive of treatment response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Treatment\u2010na\u00efve patients with OSA were prospectively recruited from the Centre for Sleep Medicine and Science at Beijing Anzhen Hospital between July 2023 and April 2025. All participants underwent 24\u2010h ABPM assessments before and after 3\u2010month CPAP therapy. Correlations between the baseline ABPM data and post\u2010CPAP changes in blood pressure were analyzed. Multivariate analysis was used to determine whether specific baseline blood pressure cutoffs independently predicted a clinically significant reduction in blood pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Good CPAP adherence (median usage: 6.1\u2009h\/night and 6.0\u2009days\/week; residual apnea\u2013hypopnea index: 1.7 events\/h) was achieved among 51 recruited patients (92.2% male, median age 40.5\u2009years). After 3 months of CPAP treatment, significant reductions were observed in nearly all blood pressure measurements. Baseline 24\u2010h mean arterial pressure (MAP) was positively correlated with the reduction in all 24\u2010h blood pressure measures, all nighttime blood pressure measures, and daytime MAP. Compared with patients with 24\u2010h MAP &lt;\u200996\u2009mmHg, those with baseline 24\u2010h MAP \u2265\u200996\u2009mmHg experienced relatively high absolute and relative reductions in all blood pressure measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Baseline 24\u2010h MAP effectively predicts blood pressure reduction following CPAP therapy in patients with OSA, demonstrating the clinical value of an ABPM\u2010guided strategy for managing patients with comorbid OSA and hypertension.<\/jats:p>\n                    <jats:p>Trial Registration: ChiCTR2300067728<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/crj.70167","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T12:32:01Z","timestamp":1768912321000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predicting Significant Blood Pressure Reduction Through Ambulatory Blood Pressure Monitoring in Patients With Obstructive Sleep Apnea Treated With Continuous Positive Airway Pressure"],"prefix":"10.1111","volume":"20","author":[{"given":"Yuanni","family":"Jiao","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Medicine Beijing Anzhen Hospital, Capital Medical University  Beijing China"},{"name":"Beijing Anzhen Hospital Centre for Sleep Medicine and Science Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hehe","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Medicine Beijing Anzhen Hospital, Capital Medical University  Beijing China"},{"name":"Beijing Anzhen Hospital Centre for Sleep Medicine and Science Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[{"name":"Beijing Anzhen Hospital Centre for Sleep Medicine and Science Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Xi","sequence":"additional","affiliation":[{"name":"Beijing Anzhen Hospital Centre for Sleep Medicine and Science Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Medicine Beijing Anzhen Hospital, Capital Medical University  Beijing China"},{"name":"Beijing Anzhen Hospital Centre for Sleep Medicine and Science Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Medicine Beijing Anzhen Hospital, Capital Medical University  Beijing China"},{"name":"Beijing Anzhen Hospital Centre for Sleep Medicine and Science Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"e_1_2_14_2_1","unstructured":"World Health Organization. \u201cHypertension \u201d World Health Organization Website. Published 2023. Accessed August 19 2025 https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/hypertension."},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.14929"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20102600(19)30198\u20105"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41440\u2010022\u201000954\u20109"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.202203\u2010260OC"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2021.101446"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00837\u20102024"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01945\u20102019"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00651\u20102017"},{"key":"e_1_2_14_11_1","unstructured":"American Academy of Sleep Medicine \u201cThe AASM Manual for the Scoring of Sleep and Associated Events \u201d American Academy of Sleep Medicine; 2023. 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