{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T16:05:35Z","timestamp":1785945935741,"version":"3.56.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370088"],"award-info":[{"award-number":["82370088"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470089"],"award-info":[{"award-number":["82470089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470090"],"award-info":[{"award-number":["82470090"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n Type IV sleep monitors offer a low\u2010burden option for obstructive sleep apnea (OSA) screening, yet their accuracy is often limited by motion artifacts and variability in signal\u2010processing methods. The PM50\u2010B is a wrist\u2010worn Type IV device that combines high\u2010sampling\u2010rate (200\u2009Hz) photoplethysmography (PPG)\u2010based oximetry with wrist actigraphy to reduce motion artifacts and employs an adaptive SpO\n 2<\/jats:sub>\n waveform\u2010based desaturation detection algorithm. This study aimed to validate the diagnostic performance of the PM50\u2010B against reference sleep studies.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n In this prospective observational study, adults with suspected OSA underwent simultaneous overnight recording with the PM50\u2010B and a reference test: in\u2010laboratory polysomnography (Type I), unattended polysomnography (Type II), or Type III home sleep apnea testing (HSAT). Oximetry and actigraphy signals were processed using a standardized workflow incorporating motion\u2010artifact attenuation, signal stabilization, and sleep\u2013wake estimation. From the SpO\n 2<\/jats:sub>\n signal, hypoxemia metrics were derived, including the oxygen desaturation index ODI2.5_5 (\u2265\u20092.5% desaturation lasting \u2265\u20095\u2009s\/h of total sleep time), cumulative time with SpO\n 2<\/jats:sub>\n \u2009<\u200990% and <\u200995% (CT90, CT95), and lowest SpO\n 2<\/jats:sub>\n . Agreement with the reference apnea\u2013hypopnea index (AHI) was assessed using intraclass correlation coefficients, and diagnostic accuracy was evaluated at clinically relevant AHI thresholds.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 475 participants were analysed (Type I,\n n<\/jats:italic>\n \u2009=\u200937; Type II,\n n<\/jats:italic>\n \u2009=\u200932; Type III,\n n<\/jats:italic>\n \u2009=\u2009406). ODI2.5_5 showed moderate\u2010to\u2010good agreement with AHI (ICC\u2009=\u20090.710) and good discrimination for moderate\u2010to\u2010severe OSA (AHI\u2009\u2265\u200915 events\/h), with an under the curve (AUC) of 0.925 (sensitivity 81.20%, specificity 91.00%). Diagnostic performance was consistent across reference modalities (AUC range, 0.928\u20130.983).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The PM50\u2010B provides clinically acceptable accuracy for OSA screening when combined with a standardized signal\u2010processing approach, particularly in comparison with Type III HSAT. ODI2.5_5 emerged as the strongest diagnostic metric, while CT90, CT95, and lowest SpO\n 2<\/jats:sub>\n provided complementary characterization of nocturnal hypoxemia.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/crj.70176","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T02:55:18Z","timestamp":1771383318000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Novel Type IV Monitoring Device With Advanced Oximetry Indicators Offers Accurate Diagnosis of Obstructive Sleep Apnea in Adults"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7714-5035","authenticated-orcid":false,"given":"Xu","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailiang","family":"Qin","sequence":"additional","affiliation":[{"name":"School of Health Science and Engineering University of Shanghai for Science and Technology Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huai","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Mechatronic Engineering and Automation Shanghai University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zilong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[{"name":"School of Mechatronic Engineering and Automation Shanghai University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanqun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University Shanghai 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