{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:47:22Z","timestamp":1789004842017,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T00:00:00Z","timestamp":1778457600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We report the case of a 25\u2010year\u2010old woman with a history of acute lymphoblastic leukemia who developed progressive dyspnea and fever following allogeneic hematopoietic stem cell transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>Despite broad\u2010spectrum empirical antimicrobial therapy, the patient's clinical condition worsened. Comprehensive diagnostic evaluation revealed human coronavirus OC43 (HCoV\u2010OC43) as the causative pathogen. Histopathological examination of lung tissue confirmed viral pneumonia. Treatment with nirmatrelvir\/ritonavir (Paxlovid) was initiated. The patient demonstrated rapid clinical improvement, with complete radiological resolution within 3\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights the potential therapeutic role of nirmatrelvir\/ritonavir in managing severe HCoV\u2010OC43 pneumonia in patients who are immunocompromised.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/crj.70196","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T08:13:08Z","timestamp":1778487188000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Severe HCoV\u2010OC43 Pneumonia in a 25\u2010Year\u2010Old Woman Following Allogeneic Hematopoietic Stem Cell Transplantation"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8879-6426","authenticated-orcid":false,"given":"Mingzhou","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Xinqiao Hospital of Third Military Medical University (Army Medical University)  Chongqing China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Disease Chongqing Public Health Emergency Medical Center  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxia","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Xinqiao Hospital of Third Military Medical University (Army Medical University)  Chongqing China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menglin","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Xinqiao Hospital, Third Military Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Xinqiao Hospital of Third Military Medical University (Army Medical University)  Chongqing China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guansong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Xinqiao Hospital of Third Military Medical University (Army Medical University)  Chongqing China"},{"name":"Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2018.01.019"},{"key":"e_1_2_12_3_1","volume-title":"Technical Consultation on Human Coronaviruses: Epidemiology and Clinical Features","author":"World Health 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