{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T11:48:14Z","timestamp":1782388094611,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2026,6]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n \n Extracorporeal carbon dioxide removal (ECCO\n 2<\/jats:sub>\n R) is a type of partial extracorporeal respiratory support with potential to reduce lung injury in patients with hypercapnic respiratory failure. We aimed to study the current practice and perceptions of ECCO\n 2<\/jats:sub>\n R and the need for an ECCO\n 2<\/jats:sub>\n R registry.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A multinational survey was conducted among clinicians who have published clinical studies on ECCO\n 2<\/jats:sub>\n R or have used ECCO\n 2<\/jats:sub>\n R within the last 5\u2009years in Europe, Asia, Oceania and the United States.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Seventy responses from 140 requests (response rate: 50%) were received from physicians across all targeted regions. ECCO\n 2<\/jats:sub>\n R is reported to be used mainly for ARDS (46%) management, followed by asthma (18%) and COPD (15%). Eighty\u2010five percent of the participants reported low case volumes (0\u201310 cases per year). Variations in the practice of ECCO\n 2<\/jats:sub>\n R were evident, including triggers for initiating ECCO\n 2<\/jats:sub>\n R, devices used, access catheter type and size, targeted blood flow rates and monitoring of anticoagulation. The most common barriers to wider use of ECCO\n 2<\/jats:sub>\n R included lack of evidence, followed by the device's costs and operational complexity. Eighty\u2010four percent (48\/57) of the respondents thought an ECCO\n 2<\/jats:sub>\n R registry would be useful, and 98% (47\/48) of the respondents reported that they would be willing to contribute to a dedicated ECCO\n 2<\/jats:sub>\n R registry.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n ECCO\n 2<\/jats:sub>\n R practices varied considerably, but most respondents agreed on the usefulness of a dedicated ECCO\n 2<\/jats:sub>\n R registry. Practice variations may be associated with suboptimal outcomes. ECCO\n 2<\/jats:sub>\n R quality indicators are needed to optimise clinical outcomes and resource utilisation.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/crj.70203","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:56:42Z","timestamp":1781614602000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Practice and Perceptions on Extracorporeal Carbon Dioxide Removal in the Current Era: A Multinational Survey"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3800-902X","authenticated-orcid":false,"given":"Ravindranath","family":"Tiruvoipati","sequence":"first","affiliation":[{"name":"Department of Intensive Care Medicine Frankston Hospital Frankston Victoria Australia"},{"name":"Division of Medicine, Peninsula Clinical School Monash University Frankston Victoria Australia"},{"name":"ANZIC\u2010RC, School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Frankston Hospital Frankston Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3805-4680","authenticated-orcid":false,"given":"Matthew E.","family":"Cove","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Respiratory and Critical Care Medicine National University Hospital Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Son","family":"Do","sequence":"additional","affiliation":[{"name":"Center for Critical Medicine, Bach Mai Hospital University of Medicine and Pharmacy, Vietnam National University Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QuangDai","family":"Huynh","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Emergency Medicine and Clinical Toxicology University of Medicine and Pharmacy Ho Chi Minh City Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon Sin Wai","family":"Ching","sequence":"additional","affiliation":[{"name":"Critical Care Medicine Unit, School of Clinical Medicine University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-021-00824-6"},{"issue":"4","key":"e_1_2_13_3_1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S1441-2772(23)00802-5","article-title":"Early Experience of a New Extracorporeal Carbon Dioxide Removal Device for Acute Hypercapnic Respiratory Failure","volume":"18","author":"Tiruvoipati R.","year":"2016","journal-title":"Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000607"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181b764d2"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-023-01269-2"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000372"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202311-2060OC"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.13374"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2022-218874"},{"issue":"33","key":"e_1_2_13_11_1","first-page":"1","article-title":"Extracorporeal Carbon Dioxide Removal Compared to Ventilation Alone in Patients With Acute Hypoxaemic Respiratory Failure: Cost\u2010Utility Analysis of the REST RCT","volume":"29","author":"Agus A.","year":"2023","journal-title":"Health Technology Assessment (Winchester)"},{"issue":"33","key":"e_1_2_13_12_1","first-page":"1","article-title":"Extracorporeal Carbon Dioxide Removal for the Treatment of Acute Hypoxaemic Respiratory Failure: The REST RCT","volume":"29","author":"McNamee J. 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