{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:03:00Z","timestamp":1785520980620,"version":"3.56.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T00:00:00Z","timestamp":1355184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The goal of this study was to assess the impact of recipient age on post\u2010transplant outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All pancreas transplants performed at <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndiana <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity between 2003 and 2011 were reviewed. Demographic data were compared using standard chi\u2010square and <jats:styled-content style=\"fixed-case\">ANOVA<\/jats:styled-content> testing. Standard <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ox regression survival analysis was performed using a direct entry method for covariates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients (n\u00a0=\u00a0405) were divided by decade: &lt;30\u00a0yr (n\u00a0=\u00a037), 30\u201339 (n\u00a0=\u00a0109), 40\u201349 (n\u00a0=\u00a0156), 50\u201359 (n\u00a0=\u00a085), and \u226560\u00a0yr of age (n\u00a0=\u00a018). Group demographics did not differ except for median ischemia time, which was between 7.0 and 8.5\u00a0h (p\u00a0=\u00a00.02). Early graft loss and one\u00a0yr graft and patient survival were similar between the groups. Long\u2010term patient survival demonstrated a trend toward decreased five\u2010yr survival with increasing recipient age (p\u00a0=\u00a0NS). Graft survival at five\u00a0yr by <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ox regression was the lowest for the &lt;30\u00a0yr group (74%), while all other groups were similar around 80% (p\u00a0=\u00a0NS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No statistically significant differences in pancreas transplant outcomes were demonstrated when recipients were stratified by recipient age. These results suggest that older recipients can successfully undergo pancreas transplantation and expect five\u2010yr outcomes similar to those seen in younger recipients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12047","type":"journal-article","created":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T11:11:26Z","timestamp":1355224286000},"source":"Crossref","is-referenced-by-count":40,"title":["Impact of recipient age on whole organ pancreas transplantation"],"prefix":"10.1111","volume":"27","author":[{"given":"Ashesh P.","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Mangus","sequence":"additional","affiliation":[{"name":"Department of Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Powelson","sequence":"additional","affiliation":[{"name":"Department of Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kannan P.","family":"Samy","sequence":"additional","affiliation":[{"name":"Department of Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim E.","family":"Taber","sequence":"additional","affiliation":[{"name":"Department of Medicine Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle L.","family":"Goble","sequence":"additional","affiliation":[{"name":"Department of Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Fridell","sequence":"additional","affiliation":[{"name":"Department of Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,11]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"Department of Health and Human Services: Administration on Aging \u2013 Aging Statistics.http:\/\/www.aoa.gov\/aoaroot\/aging_statistics\/index.aspx updated 9\/1\/2011."},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60667-8"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp681"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2009.00845.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181891cd6"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(97)01275-X"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2010.01172.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03095.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000135461.16794.4D"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.03.038"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318187b978"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2003.09.006"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2009.00996.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000228904.01482.88"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181f65c7d"},{"key":"e_1_2_5_17_1","unstructured":"GruessnerAC SutherlandDE GruessnerRW.Increased risk of immunological graft loss for younger recipients of a pancreas transplant. 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