{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:50:44Z","timestamp":1761630644438},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T00:00:00Z","timestamp":1364256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Kidneys from pediatric donors weighing &lt;10\u00a0kg are preferably transplanted en bloc, while kidneys from donors weighing &gt;15\u00a0kg can be safely transplanted as single kidneys. However, single kidney transplantation from donors weighing 10\u201314\u00a0kg is controversial and has not been well investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed the outcome of 15 recipients of single kidneys from donors weighing 10\u201314\u00a0kg (study group) with 40 recipients receiving an allograft from ideal deceased donors (control group).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After a follow\u2010up of three\u00a0yr, death\u2010censored graft survival was 100% in both groups. The calculated creatinine clearance was lower in the study group at six\u00a0months (53 vs. 71\u00a0mL\/min; p\u00a0=\u00a00.01) and similar at 12\u00a0months (68 vs. 68\u00a0mL\/min; p\u00a0=\u00a00.48), 24\u00a0months (81 vs. 70\u00a0mL\/min; p\u00a0=\u00a00.58), and 36\u00a0months (74 vs. 69\u00a0mL\/min; p\u00a0=\u00a00.59). Urinary albumin\/creatinine ratios were comparable between the two groups up to two\u00a0yr. At three\u00a0yr, urinary albumin\/creatinine ratios were higher in the study group than the control group (10.5 vs. 0.9\u00a0mg\/mmol; p\u00a0=\u00a00.007). Surveillance biopsies at three and six\u00a0months post\u2010transplant revealed no evidence for focal segmental glomerulosclerosis in the study group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Transplantation of single pediatric kidneys from donors weighing 10\u201314\u00a0kg into adult recipients provides excellent intermediate\u2010term outcomes. Low\u2010grade albuminuria, three\u00a0yr post\u2010transplant, might indicate late\u2010onset hyperfiltration injury.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12115","type":"journal-article","created":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T07:18:44Z","timestamp":1364282324000},"source":"Crossref","is-referenced-by-count":6,"title":["Intermediate\u2010term outcome of single kidney grafts from pediatric donors weighing 10\u201314\u00a0kg in adult recipients"],"prefix":"10.1111","volume":"27","author":[{"given":"Isabel","family":"Gr\u00f6schl","sequence":"first","affiliation":[{"name":"Clinic for Transplantation Immunology and Nephrology University Hospital Basel Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Wolff","sequence":"additional","affiliation":[{"name":"Vascular Surgery Centre University Hospital Basel Basel 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