{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T10:54:51Z","timestamp":1775991291347,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T00:00:00Z","timestamp":1375920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Kidney transplant recipients are at a high risk of opportunistic infection. The aims of this study were to describe the epidemiology, clinical features, and prognosis of abdominal tuberculosis (<jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content>) in kidney transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All cases of abdominal <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content> that occurred in kidney transplant recipients at our center between 1998 and 2010 were retrospectively reviewed. Detailed demographic data, clinical profile information, and the treatment response were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 7833 kidney transplantations performed during the study period, eight patients (0.1%) developed abdominal <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content>. There were four men and four women in this group. The mean age of the patients was 44\u00a0\u00b1\u00a012\u00a0yr. The time from kidney transplantation to <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content> was 6.7\u00a0\u00b1\u00a03.4\u00a0yr. The symptoms were weight loss (87.5%), diarrhea (87.5%), fever (75%), abdominal pain (62.5%), and lower gastrointestinal bleeding (37.5%). The delay between the identification of the clinical symptoms and the diagnosis was an average of six\u00a0months. The diagnosis was confirmed histopathologically for most patients. The cecum and ascending colon were the most common sites involved. Two patients required surgical intervention. Five patients received a 4\u2010drug regimen, and three had hepatotoxicity. The median length of antituberculous therapy was nine (6\u201312)\u00a0months. Five patients lost their graft. Overall, the hospital mortality was 12.5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Kidney transplantation increases the risk of <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content>, particularly as an extrapulmonary disease. The symptoms of infection are often attenuated, leading to delayed diagnosis. Therefore, a careful approach to the patient and supportive data are necessary to make the final and timely diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12210","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T09:33:49Z","timestamp":1375954429000},"source":"Crossref","is-referenced-by-count":7,"title":["Abdominal tuberculosis following kidney transplantation: clinicopathologic features and follow\u2010up in a unique case series"],"prefix":"10.1111","volume":"27","author":[{"given":"Ana","family":"Rocha","sequence":"first","affiliation":[{"name":"Department of Nephrology Hospital de Santo Ant\u00f3nio Centro Hospitalar do Porto Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laercio","family":"Louren\u00e7o","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital do Rim S\u00e3o Paulo Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laila","family":"Viana","sequence":"additional","affiliation":[{"name":"Department of Nephrology Hospital do Rim S\u00e3o Paulo Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Taver","sequence":"additional","affiliation":[{"name":"Department of Nephrology Hospital do Rim S\u00e3o Paulo Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Gaspar","sequence":"additional","affiliation":[{"name":"Department of Nephrology Hospital do Rim S\u00e3o Paulo Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Osmar","family":"Medina\u2010Pestana","sequence":"additional","affiliation":[{"name":"Department of Nephrology Hospital do Rim S\u00e3o Paulo Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01853.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000188689.41785.d8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/427692"},{"key":"e_1_2_6_5_1","first-page":"169","article-title":"Clinicopathological profile of patients with abdominal tuberculosis","volume":"9","author":"Miah AR","year":"2011","journal-title":"J Nepal Health Res Counc"},{"key":"e_1_2_6_6_1","first-page":"509","article-title":"Abdominal tuberculosis: analysis of clinical features and outcome of adult patients in southern Taiwan","volume":"32","author":"Hu ML","year":"2009","journal-title":"Chang Gung Med J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1097\/MEG.0b013e32834a9470","article-title":"Intestinal tuberculosis: a diagnostic challenge\u2013case report and review of the literature","volume":"23","author":"Giouleme O","year":"2011","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"e_1_2_6_8_1","first-page":"107","article-title":"More than 1,000 kidney transplants in a single year by the \u201cHospital do Rim\u201d Group in Sao Paulo\u2010 Brazil","volume":"26","author":"Medina\u2010Pestana JO","year":"2010","journal-title":"Clin Transpl"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2009.00475.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/599035"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh691"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00545.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2012-201756"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00114810"},{"issue":"4","key":"e_1_2_6_15_1","first-page":"39","article-title":"European best practice guidelines for renal transplantation. Section IV: long\u2010term management of the transplant recipient. IV.7.2. Late infections. Tuberculosis","volume":"17","author":"EBPG Expert Group on Renal Transplantation","year":"2002","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.03.013"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.77236"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.78063"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.6002\/ect.2011.0200"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.4.16141"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2011.12.065"},{"key":"e_1_2_6_22_1","first-page":"638","article-title":"Gastrointestinal tuberculosis","volume":"50","author":"Chong VH","year":"2009","journal-title":"Singapore Med J"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00874-09"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T06:51:31Z","timestamp":1696402291000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,8]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1111\/ctr.12210"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12210","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,8]]}}}