{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T23:41:48Z","timestamp":1774050108858,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T00:00:00Z","timestamp":1379548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Obesity is a major epidemic and may present a significant barrier to living kidney donation. The purpose of our study was to determine the frequency of obesity as an exclusion factor and assess how often these donors lose weight and donate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single center, retrospective analysis of 104 potential living kidney donors between 2008 and 2012.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 104 donors, 19 (18%) had a normal body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) of &lt;25. Eighty\u2010five of the 104 (82%) donors spanned the overweight to morbidly obese classifications. Thirty\u2010eight (37%) were overweight (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> 25\u201329.9). Twenty\u2010four (23%) were categorized as class I obesity (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> 30\u201334.9), 17 (16%) as class <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> obesity (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> 35\u201339.9), and six (6%) as class <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> obesity (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> &gt;40). There were a total of 23 donors (22%) who were considered moderately and morbidly obese (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> &gt;35). Of these, only three (13%) succeeded at losing weight and donating.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Obesity may be a frequent barrier to living kidney donation, directly leading to exclusion as a potential kidney donor in about one in five instances. Successful weight loss leading to donation appears to be infrequent, suggesting need to address obesity in the donor population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12246","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T14:03:29Z","timestamp":1381241009000},"page":"882-887","source":"Crossref","is-referenced-by-count":22,"title":["Obesity as a barrier to living kidney donation: a center\u2010based analysis"],"prefix":"10.1111","volume":"27","author":[{"given":"Mala","family":"Sachdeva","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Medicine Hofstra North Shore\u2010LIJ School of Medicine North Shore\u2010LIJ Health System Great Neck NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Sunday","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Feinstein Institute for Medical Research Manhasset NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ezra","family":"Israel","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine Hofstra North Shore\u2010LIJ School of Medicine North Shore\u2010LIJ Health System Great Neck NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeny","family":"Varghese","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine Hofstra North Shore\u2010LIJ School of Medicine North Shore\u2010LIJ Health System Great Neck NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Rosen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Feinstein Institute for Medical Research Manhasset NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhu","family":"Bhaskaran","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine Hofstra North Shore\u2010LIJ School of Medicine North Shore\u2010LIJ Health System Great Neck NY USA"},{"name":"Department of Surgery Hofstra North Shore\u2010LIJ School of Medicine North Shore\u2010LIJ Health System Manhasset NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernesto P.","family":"Molmenti","sequence":"additional","affiliation":[{"name":"Department of Surgery Hofstra North Shore\u2010LIJ School of Medicine North Shore\u2010LIJ Health System Manhasset NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Mattana","sequence":"additional","affiliation":[{"name":"Department of Medicine Winthrop University Hospital Mineola NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.2014"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2011.10.026"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.S2.518"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-1-200601030-00006"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804883"},{"key":"e_1_2_5_7_1","unstructured":"Organ Procurement Transplantation Network.http:\/\/optn.transplant.hrsa.gov\/latestData\/rptData.asp(Accessed March 2013)."},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01932.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2010.01336.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2009.01188.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01510210"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199911270-00011"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.00791.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181b27a17"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181f6a058"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01350209"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2000.00384.x"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12246","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T05:14:15Z","timestamp":1696396455000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,19]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/ctr.12246"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12246","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,19]]}}}