{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:27:14Z","timestamp":1790083634897,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T00:00:00Z","timestamp":1387324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This prospective observational cohort study is an extension of a previous study reporting effects of cytomegalovirus (<jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>) on graft and patient survival in 471 patients who underwent kidney transplantation between 1994 and 1997. <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> pp65 antigen was measured every 7\u201314\u00a0d during the first three\u00a0months after transplantation, given as number of <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> pp65\u2010positive cells per 10<jats:sup>5<\/jats:sup> leukocytes. A positive test was defined as <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection. None of the patients received <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> prophylaxis or preemptive treatment. During a median of 13.7 (7.1\u201314.9) yr, the number of death\u2010censored graft losses was 118 (25%) and of patient deaths 224 (48%). <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection was an independent significant risk factor for mortality in multivariate analysis (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a01.453, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.033\u20132.045, p\u00a0=\u00a00.032), adjusting for patient and donor age, preemptive transplantation, <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">DR<\/jats:styled-content> and \u2010<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> mismatches, living donor, acute rejection during the first three\u00a0months, donor\u2013recipient <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> IgG antibody status and diabetic nephropathy. In univariate analysis, <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection was significantly associated with death\u2010censored graft loss but the association was not significant in multivariate model. <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection early after kidney transplantation is a predictor of overall mortality but not of death\u2010censored graft loss after a median observation period of 13.7\u00a0yr.<\/jats:p>","DOI":"10.1111\/ctr.12288","type":"journal-article","created":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T13:57:40Z","timestamp":1387375060000},"page":"120-126","source":"Crossref","is-referenced-by-count":43,"title":["The impact of early cytomegalovirus infection after kidney transplantation on long\u2010term graft and patient survival"],"prefix":"10.1111","volume":"28","author":[{"given":"Yuliya V.","family":"Smedbr\u00e5ten","sequence":"first","affiliation":[{"name":"Department of Nephrology Ullev\u00e5l Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solbj\u00f8rg","family":"Sagedal","sequence":"additional","affiliation":[{"name":"Department of Nephrology Ullev\u00e5l Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torbj\u00f8rn","family":"Leivestad","sequence":"additional","affiliation":[{"name":"Department of Transplant Medicine Rikshospitalet Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geir","family":"Mj\u00f8en","sequence":"additional","affiliation":[{"name":"Department of Nephrology Ullev\u00e5l Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e5re","family":"Osnes","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry and Psychosomatic Medicine Rikshospitalet Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halvor","family":"Rollag","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology Rikshospitalet Oslo University Hospital Oslo Norway"},{"name":"Faculty of Medicine University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna V.","family":"Reis\u00e6ter","sequence":"additional","affiliation":[{"name":"Department of Transplant Medicine Rikshospitalet Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aksel","family":"Foss","sequence":"additional","affiliation":[{"name":"Department of Transplant Medicine Rikshospitalet Oslo University Hospital Oslo Norway"},{"name":"Faculty of Medicine University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Os","sequence":"additional","affiliation":[{"name":"Department of Nephrology Ullev\u00e5l Oslo University Hospital Oslo Norway"},{"name":"Faculty of Medicine University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Department of Transplant Medicine Rikshospitalet Oslo University Hospital Oslo Norway"},{"name":"Faculty of Medicine University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200010270-00007"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-004-1499-z"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02133.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00451.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000230460.42558.b0"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00735.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2006.00639.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2002.20907.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-011-2105-9"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2003.00010.x"},{"key":"e_1_2_6_13_1","first-page":"15","article-title":"Effect of donor recipient age match on survival after first deceased donor renal transplantation","volume":"2004","author":"Keith DS","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e32833bd3b5"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02617.x"},{"key":"e_1_2_6_16_1","first-page":"68","article-title":"Association between cytomegalovirus disease and chronic rejection in kidney transplant recipients","volume":"1999","author":"Humar A","year":"1879","journal-title":"Transplantation"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12288","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T12:26:16Z","timestamp":1696335976000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,18]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/ctr.12288"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12288","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,18]]}}}