{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:47:53Z","timestamp":1789580873896,"version":"build-2803163510"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T00:00:00Z","timestamp":1387843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Previous studies have indicated <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>\u2010shaped associations between blood pressure (<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) and mortality in dialysis patients. We hypothesized that a similar association exists between pre\u2010transplant <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and post\u2010transplant outcomes in dialysis patients who undergo successful kidney transplantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from the <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cientific <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>egistry of <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ransplant <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>ecipients<\/jats:italic> were linked to the five\u2010yr cohort of a large dialysis organization in the <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>nited <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tates. We identified all dialysis patients who received a kidney transplant during this period. Unadjusted and multivariate adjusted predictors of transplant outcomes were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 13\u00a0881 patients included in our study were 47\u00a0\u00b1\u00a014\u00a0yr old and included 42% women. There was no association between pre\u2010transplant systolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and post\u2010transplant mortality, although a decreased risk trend was observed in those with low post\u2010dialysis systolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>. Compared to patients with pre\u2010dialysis diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> 70 to &lt;80\u00a0mmHg, patients with pre\u2010dialysis diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> &lt;50\u00a0mmHg experienced lower risk of post\u2010transplant death (hazard ratios [<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>]: 0.74, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.55\u20130.99). However, compared to patients with post\u2010dialysis diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> 70 to &lt;80\u00a0mmHg, patients with post\u2010dialysis diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> \u2265100\u00a0mmHg experienced higher risk of death (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>: 3.50, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.57\u20137.84). In addition, very low (&lt;50\u00a0mmHg for diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and &lt;110\u00a0mmHg for systolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) pre\u2010transplant <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> was associated with lower risk of graft loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Low post\u2010dialysis systolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and low pre\u2010dialysis diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> are associated with lower post\u2010transplant risk of death, whereas very high post\u2010dialysis diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> is associated with higher mortality in kidney transplant recipients. <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> variations in dialysis patients prior to kidney transplantation may have a bearing on post\u2010transplant outcome, which warrants additional studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12292","type":"journal-article","created":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T06:51:01Z","timestamp":1387867861000},"page":"166-176","source":"Crossref","is-referenced-by-count":13,"title":["Association of pre\u2010transplant blood pressure with post\u2010transplant outcomes"],"prefix":"10.1111","volume":"28","author":[{"given":"Miklos Z.","family":"Molnar","sequence":"first","affiliation":[{"name":"Division of Nephrology &amp; Hypertension University of California Irvine Medical Center  Orange CA USA"},{"name":"Harold Simmons Center for Chronic Disease Research &amp; Epidemiology Los Angeles Biomedical Research Institute at Harbor\u2010UCLA Medical Center Torrance CA USA"},{"name":"Division of Nephrology Department of Medicine University Health Network University of Toronto  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"3rd","given":"Clarence E.","family":"Foster","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery University of California Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Sim","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Remport","sequence":"additional","affiliation":[{"name":"Szent Imre Hospital Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahesh","family":"Krishnan","sequence":"additional","affiliation":[{"name":"DaVita, Inc. 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