{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:15:24Z","timestamp":1772115324552,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,19]],"date-time":"2014-02-19T00:00:00Z","timestamp":1392768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Low birthweight is linked to hypertension, chronic kidney disease and even end\u2010stage renal disease. We hypothesized that living kidney donors born with lower birthweight may be at increased risk of hypertension, albuminuria, or reduced <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content> beyond what is typical following uninephrectomy. Two hundred fifty\u2010seven living kidney donors who donated at the University of Minnesota between 1967 and 2005 underwent iohexol <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content> and urinary albumin excretion measurements. Predictors of iohexol <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content> &lt;60\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>, albuminuria, and hypertension were examined using logistic regression. Predictors examined include age at <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content> measurement, time since donation, <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, gender, serum creatinine level (at donation and <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content> measurement), systolic and diastolic blood pressure, race, and birthweight. The latter was obtained through self\u2010report and verified through birth certificates and family members. Older age, higher <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, and time from donation were associated with reduced <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content>. Older age and higher <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> were also associated with hypertension. Birthweight was not associated with <jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content> &lt;60\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>: <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=0.70, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> (0.28, 1.74), p\u00a0=\u00a00.45 or hypertension: <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=0.92, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> (0.46, 1.84), p\u00a0=\u00a00.82 but was associated with albuminuria: <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>=0.37, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> (0.15, 0.92), p\u00a0=\u00a00.03. These data further strengthen the link between low birthweight and potential adverse renal outcomes.<\/jats:p>","DOI":"10.1111\/ctr.12321","type":"journal-article","created":{"date-parts":[[2014,2,19]],"date-time":"2014-02-19T05:42:44Z","timestamp":1392788564000},"page":"361-367","source":"Crossref","is-referenced-by-count":23,"title":["Low birthweight and risk of albuminuria in living kidney donors"],"prefix":"10.1111","volume":"28","author":[{"given":"Danielle","family":"Berglund","sequence":"first","affiliation":[{"name":"Department of Surgery University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"MacDonald","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Jackson","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Spong","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naim","family":"Issa","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Kukla","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Reule","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Weber","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur J.","family":"Matas","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan N.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0b013e32834bd72b"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804883"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.237"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92683-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1995.355"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199710150-00007"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200108150-00015"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000250728.73268.e3"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318192dc95"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2012.01439.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.09712.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/760580"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/136942"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/30.6.1233"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00225.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00484.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199809000-00009"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/1.4.335"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2011.10.006"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2008.12.042"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.05.017"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1992.tb13726.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.9.1264"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(98)00197-7"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200018070-00002"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-6193-9.10022-3"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007020252"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-009-1371-y"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn431"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.00451.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0309"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/152.7.597"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2004090783"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2009.201"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008070730"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp205"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.54.8.639"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.76.11.1350"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/152.7.609"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-6193-9.10020-X"},{"key":"e_1_2_7_42_1","first-page":"411","article-title":"Race, clinical factors and pre\u2010term birth in a low\u2010income urban setting","volume":"10","author":"Orr ST","year":"2000","journal-title":"Ethn Dis"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12321","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12321","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T08:42:14Z","timestamp":1695544934000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,19]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/ctr.12321"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12321","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,19]]}}}