{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T22:22:32Z","timestamp":1783030952115,"version":"3.54.6"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T00:00:00Z","timestamp":1407715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pregnancy after solid organ transplant is a significant priority for transplant recipients but how patients report being counseled is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a single\u2010center retrospective cohort study and telephone survey of female patients ages 18\u201349 at the time of kidney, pancreas, or liver transplant from 2000 to 2012 (n\u00a0=\u00a0532). Data on pregnancy counseling, fertility, and maternal, fetal\u2010 and transplant\u2010specific outcomes were collected. Multivariate Cox models assessed the impact of pregnancy on graft\u2010specific outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The survey response rate was 29% (n\u00a0=\u00a0152). One\u2010third (n\u00a0=\u00a051) of women were actively counseled against pregnancy by one or more providers. A total of 17 pregnancies occurred among nine patients (5.9%), with 47% live births, 47% early embryonic demises, 5.9% stillbirths. Of live births, 50% were premature. Gestational complications, including diabetes, hypertension, and preeclampsia were present in 88% of mothers. Pregnancy after transplant was associated with higher rates of acute rejection than nulliparous transplant recipients (33% vs. 5.6%, p\u00a0=\u00a00.07) but did not significantly affect graft survival (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a01.00, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.99\u20131.01), after stratifying by organ and adjusting for clinical factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggests that transplant patients are being counseled against pregnancy despite acceptable risks of complications and no specific effects on long\u2010term graft function.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12393","type":"journal-article","created":{"date-parts":[[2014,6,17]],"date-time":"2014-06-17T16:49:40Z","timestamp":1403023780000},"page":"937-945","source":"Crossref","is-referenced-by-count":38,"title":["Preconception counseling, fertility, and pregnancy complications after abdominal organ transplantation: a survey and cohort study of 532 recipients"],"prefix":"10.1111","volume":"28","author":[{"given":"Devon M.","family":"Rupley","sequence":"first","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison M.","family":"Janda","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven R.","family":"Kapeles","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim M.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Berman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit K.","family":"Mathur","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Department of Surgery Mayo Clinic Phoenix AZ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra050431"},{"key":"e_1_2_5_3_1","volume-title":"National Transplant Registry","author":"Armenti VT","year":"2012"},{"key":"e_1_2_5_4_1","first-page":"131","article-title":"Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation","volume":"20","author":"Armenti VT","year":"2003","journal-title":"Clin Transplant"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23416"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03656.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.09.175"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.09.012"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.7182\/prtr.16.2.j3324t64t6517u76"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12579"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12580"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12581"},{"key":"e_1_2_5_13_1","first-page":"792","article-title":"Pregnancy in kidney transplantation: satisfactory outcomes and harsh realities","volume":"16","author":"Stratta P","year":"2003","journal-title":"J Nephrol"},{"key":"e_1_2_5_14_1","unstructured":"Centers for Disease Control and Prevention. Available from:http:\/\/www.cdc.gov\/reproductivehealth\/maternalinfanthealth\/pretermbirth.htm. [cited 10\/30\/2013] 2013."},{"issue":"3","key":"e_1_2_5_15_1","first-page":"332","article-title":"Intrauterine growth retardation (IUGR): epidemiology and etiology","volume":"6","author":"Romo A","year":"2009","journal-title":"Pediatr Endocrinol Rev"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)35237-9"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.00969.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318277e318"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.02.105"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1341-8076.2003.00106.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/85.2.584S"},{"key":"e_1_2_5_22_1","first-page":"1","article-title":"Births: final data for 2011","volume":"62","author":"Martin JA","year":"2013","journal-title":"Natl Vital Stat Rep"},{"key":"e_1_2_5_23_1","unstructured":"Centers for Disease Control and Prevention. Available from:http:\/\/www.cdc.gov\/asthma\/asthmadata.htm. [cited 2\/16\/2014] 2014."},{"key":"e_1_2_5_24_1","unstructured":"Centers for Disease Control and Prevention. Available from:http:\/\/www.cdc.gov\/features\/dsdev_disabilities\/[cited 2\/16\/2014] 2014."}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12393","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:21:19Z","timestamp":1695572479000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,11]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1111\/ctr.12393"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12393","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,11]]}}}