{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T17:18:43Z","timestamp":1771607923381,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,12,7]],"date-time":"2014-12-07T00:00:00Z","timestamp":1417910400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001258","name":"Roche Organ Transplant Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001258","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2014,12]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>The Indiana Organ Procurement Organization (IOPO<\/jats:styled-content>) utilizes preoperative bedside liver biopsies in certain extended\u2010criteria donors (ECD<\/jats:styled-content>s), obtained by the on\u2010site coordinator, to determine the utility of pursuing donation. This study reports the clinical and financial outcomes for this management strategy.<\/jats:p><\/jats:sec>Methods<\/jats:title>All bedside liver biopsies obtained in ECD<\/jats:styled-content>s over a five\u2010yr period were reviewed. Study variables included the following: indication for biopsy, biopsy results, taking the case to the operating room, transplantation of the donor liver, and graft survival. All biopsies were processed at a single university center.<\/jats:p><\/jats:sec>Results<\/jats:title>There were 110 donors biopsied. Primary indications included the following: old age (29%), extensive\/current alcohol abuse (26%), hepatitis C\u2010positive serology (21%), obesity (25%), and severely elevated liver function enzymes (18%). Biopsy results demonstrated a potentially transplantable liver in 73 cases (66%), all of whom were taken to the OR<\/jats:styled-content> (while 37 ruled out for donation based upon liver biopsy [34%]). Of all biopsied livers, 49 ultimately were transplanted (45%). Intra\u2010operative decisions included the following: transplant 51\/73 (70%), surgeon decision to exclude 20\/73 (27%), nonuse due to finding of malignancy two (3%).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Bedside liver biopsy may be a valuable tool to determine the utility in pursuing donation in ECD<\/jats:styled-content>s, particularly with liver\u2010only donors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12461","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T15:31:33Z","timestamp":1410276693000},"page":"1358-1364","source":"Crossref","is-referenced-by-count":17,"title":["Utility of pre\u2010procurement bedside liver biopsy in the deceased extended\u2010criteria liver donor"],"prefix":"10.1111","volume":"28","author":[{"given":"Richard S.","family":"Mangus","sequence":"first","affiliation":[{"name":"Transplant Division Department of Surgery Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim C.","family":"Borup","sequence":"additional","affiliation":[{"name":"Transplant Division Department of Surgery Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Popa","sequence":"additional","affiliation":[{"name":"Indiana Organ Procurement Organization Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romil","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of Pathology Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Cummings","sequence":"additional","affiliation":[{"name":"Department of Pathology Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Joseph","family":"Tector","sequence":"additional","affiliation":[{"name":"Transplant Division Department of Surgery Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000183973.49899.b1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000234896.18207.fa"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2003.50105"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21726"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0012.2001.150109.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21419"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21372"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12461","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12461","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T21:17:27Z","timestamp":1695503847000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/ctr.12461"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12461","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12]]}}}