{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T19:42:28Z","timestamp":1766086948567},"reference-count":49,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T00:00:00Z","timestamp":1413417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective single\u2010center review of 884 deceased donor (<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>) kidney transplants (<jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>s) in patients (pts) aged \u226540 yr.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and four (11.8%) pts were \u226570 (mean 74), 286 (32.3%) were 60\u201369 (mean 64), and 494 (55.9%) were 40\u201359 (mean 51) yr of age; the proportion receiving expanded criteria donor (<jats:styled-content style=\"fixed-case\">ECD<\/jats:styled-content>) kidneys were 66%, 49%, and 30%, respectively (p\u00a0&lt;\u00a00.001). Mean waiting time (15\u00a0months) was shorter for pts \u226570\u00a0yr compared to the other two groups combined (23\u00a0months, p\u00a0=\u00a00.002). With mean follow\u2010up ranging from 54 to 70\u00a0months, actual pt (81% vs. 72%, p\u00a0=\u00a00.002) and graft (66% vs. 58.5%, p\u00a0=\u00a00.03) survival rates were higher in the younger compared to the two older groups, whereas death\u2010censored graft survival was similar (76% vs. 73%, p\u00a0=\u00a0NS). The incidence of death with a functioning graft correlated with older recipient age group, increasing from 13% to 18% to 23% (p\u00a0=\u00a00.01). The incidence of delayed graft function was similar (31.8% overall), and renal function, morbidity, and resource utilization were similar among groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>By directing <jats:styled-content style=\"fixed-case\">ECD<\/jats:styled-content> kidneys to selected older pts, waiting times are reduced and censored survival outcomes are similar to middle\u2010aged patients, suggesting that matching strategies for graft and patient lifespan are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12463","type":"journal-article","created":{"date-parts":[[2014,9,24]],"date-time":"2014-09-24T08:01:21Z","timestamp":1411545681000},"page":"1372-1382","source":"Crossref","is-referenced-by-count":28,"title":["Influence of recipient age on deceased donor kidney transplant outcomes in the expanded criteria donor era"],"prefix":"10.1111","volume":"28","author":[{"given":"Yousef","family":"Al\u2010Shraideh","sequence":"first","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umar","family":"Farooq","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan C.","family":"Farney","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amudha","family":"Palanisamy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Rogers","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Orlando","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber","family":"Reeves\u2010Daniel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Doares","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Kaczmorski","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Gautreaux","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samy S.","family":"Iskandar","sequence":"additional","affiliation":[{"name":"Department of Pathology Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Hairston","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Brim","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Mangus","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Stratta","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wake Forest School of Medicine Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12579"},{"key":"e_1_2_6_3_1","unstructured":"U.S. Renal Data System USRDS 2013 Annual Data Report: Atlas of Chronic Kidney Disease and End\u2010Stage Renal Disease in the United States National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Bethesda MD 2013. Available at:http:\/\/www.usrds.org\/atlas.aspx"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04245.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2012.08.049"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01280209"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04259.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000042166.70351.57"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000120370.35927.40"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00066.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.00410.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182a688e5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2013.105"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12106"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04323.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000438026.03958.7b"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.3.s4.11.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000044171.97375.61"},{"key":"e_1_2_6_19_1","first-page":"726","article-title":"Kidney transplantation in patients aged sixty years and older","volume":"108","author":"Schulak JA","year":"1990","journal-title":"Surgery"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00622.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1681\/ASN.V1341067","article-title":"Matching older kidneys with older patients does not improve allograft survival","volume":"13","author":"Kasiske BL","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200204270-00032"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000119572.02053.F2"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200207270-00021"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2002.50002.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000216284.81604.d4"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000216302.43776.1a"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2007.08.005"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.07.004"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181b4acfb"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00579.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.21.2726"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.4.824"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200003150-00019"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912023412303"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V123589"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200003150-00020"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01318.x"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01311.x"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/15.3.315"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.05.037"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.08731010"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181a4b67d"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181f65c7d"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03798.x"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/15.5.696"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2002.20713.x"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.01.028"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2011.1229"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12300"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12463","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12463","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T21:17:31Z","timestamp":1695503851000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,16]]},"references-count":49,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/ctr.12463"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12463","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,16]]}}}