{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:06:52Z","timestamp":1792019212781,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T00:00:00Z","timestamp":1424649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Biliary complications are a leading source of surgical morbidity following orthotopic liver transplantation (<jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined how prophylactic internal biliary stent placement during <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> affected post\u2010transplant morbidity and mortality in a single\u2010center retrospective cohort study of 513 recipients (2006\u20132012). Recipient and donor covariates were collected. Biliary complications included major and minor anastomotic leaks, strictures, or stenoses. Multivariate regression models were created to estimate how operative biliary stents affected outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>About 87.3% (n\u00a0=\u00a0448) of recipients had a duct\u2010to\u2010duct biliary anastomosis, and 43.1% (n\u00a0=\u00a0221) had biliary stents placed. The biliary complication rate was &lt;15% at five\u00a0yr, and 44.8% (n\u00a0=\u00a0230) overall. Stenting was not protective from anastomotic biliary complications (p\u00a0=\u00a00.06). Stenting was associated with a 74% higher adjusted risk of needing multiple endoscopic retrograde cholangiographies (<jats:styled-content style=\"fixed-case\">ERC<\/jats:styled-content>s; <jats:styled-content style=\"fixed-case\">o<\/jats:styled-content>dds <jats:styled-content style=\"fixed-case\">r<\/jats:styled-content>atio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>] 1.74, p\u00a0=\u00a00.011), and trended toward a lower adjusted risk for repetitive percutaneous transhepatic cholangiography (<jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content>s; <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.56, p\u00a0=\u00a00.063). Stenting had no effect on the cumulative freedom from biliary complications (p\u00a0=\u00a00.94). Biliary complications were associated with mortality (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 1.86, p\u00a0=\u00a00.014) and was unaffected by stenting (a<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a00.72, p\u00a0=\u00a00.246).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Biliary stenting during <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> does not deter biliary complications and is associated with higher risk of multiple invasive biliary interventions, particularly ERCs. Surgeons should evaluate the utility of biliary stents at OLT within this context.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12518","type":"journal-article","created":{"date-parts":[[2015,1,21]],"date-time":"2015-01-21T12:22:59Z","timestamp":1421842979000},"page":"327-335","source":"Crossref","is-referenced-by-count":25,"title":["Internal biliary stenting during orthotopic liver transplantation: anastomotic complications, post\u2010transplant biliary interventions, and survival"],"prefix":"10.1111","volume":"29","author":[{"given":"Amit K.","family":"Mathur","sequence":"first","affiliation":[{"name":"Division of Transplant Surgery Department of Surgery Mayo Clinic Arizona Phoenix AZ USA"},{"name":"Mayo Clinic Robert D. and Patricia E. Kern Center for Science of Health Care Delivery Charleston SC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish N.","family":"Nadig","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Department of Surgery Medical University of South Carolina Charleston SC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Kingman","sequence":"additional","affiliation":[{"name":"Department of Surgery University of California at Los Angeles Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dustin","family":"Lee","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Kinkade","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Sonnenday","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore H.","family":"Welling","sequence":"additional","affiliation":[{"name":"Section of Transplantation Surgery Department of Surgery University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2012.05.008"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2010.01202.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000197"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21354"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2010.01146.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01575.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03293.x"},{"key":"e_1_2_5_9_1","first-page":"1194","article-title":"Impact of graft steatosis on the post\u2010transplantation biliary complications for living donor liver transplant recipients in China","volume":"59","author":"Li 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