{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T01:36:12Z","timestamp":1765157772711},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T00:00:00Z","timestamp":1429142400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The outcome of <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>\u2010incompatible kidney transplantation (<jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>i <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>) has improved and is now comparable to that of <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>\u2010compatible kidney transplantation (<jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>c <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>). However, <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>i <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> may be associated with a higher risk of postoperative bleeding than <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>c <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy patients with <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>i <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> were divided into a bleeding group (n\u00a0=\u00a09) and non\u2010bleeding group (n\u00a0=\u00a061). General, immunologic, and hematological characteristics were compared to identify the risk factors for postoperative bleeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pre\u2010emptive transplantation and a high pre\u2010transplant blood urea nitrogen level were more common in the bleeding group (p\u00a0=\u00a00.0176 and 0.023, respectively). A high anti\u2010<jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content> antibody titer after plasmapheresis (median, \u226516; p\u00a0=\u00a00.0226), a low platelet count of \u2264100\u00a0000\/mm<jats:sup>3<\/jats:sup> after plasmapheresis (p\u00a0=\u00a00.0289), a prolonged activated partial thromboplastin time (p\u00a0=\u00a00.0073), and impaired platelet function (p\u00a0=\u00a00.0274) were associated with an increased risk of bleeding after <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>i <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Postoperative bleeding after <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>i <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> was difficult to control and increased the risk of immediate graft loss (p\u00a0=\u00a00.015). Our results suggest that changes in coagulability associated with uremia and plasmapheresis may increase the risk of bleeding after <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>i <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12525","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T13:25:11Z","timestamp":1422969911000},"page":"365-372","source":"Crossref","is-referenced-by-count":19,"title":["Risk factors for postoperative bleeding in ABO\u2010incompatible kidney transplantation"],"prefix":"10.1111","volume":"29","author":[{"given":"Mi Hyeong","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Vascular and Transplant Surgery Department of Surgery Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang Woong","family":"Jun","sequence":"additional","affiliation":[{"name":"Division of Vascular and Transplant Surgery Department of Surgery Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Kye","family":"Hwang","sequence":"additional","affiliation":[{"name":"Division of Vascular and Transplant Surgery Department of Surgery Daejeon St. Mary's Hospital, College of Medicine The Catholic University of Korea Daejeon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Il","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Vascular and Transplant Surgery Department of Surgery Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byung Ha","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seocho\u2010gu Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bum Soon","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seocho\u2010gu Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seocho\u2010gu Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chul Woo","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seocho\u2010gu Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In Sung","family":"Moon","sequence":"additional","affiliation":[{"name":"Division of Vascular and Transplant Surgery Department of Surgery Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,16]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Annual report of the transplant 2012. 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