{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T05:47:55Z","timestamp":1695620875981},"reference-count":16,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,7,20]],"date-time":"2015-07-20T00:00:00Z","timestamp":1437350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Severe systemic hypertension (<jats:styled-content style=\"fixed-case\">HTN<\/jats:styled-content>) is a risk factor for perioperative cardiovascular complications; however, its impact at the time of kidney transplantation (<jats:styled-content style=\"fixed-case\">KTX<\/jats:styled-content>) is not well defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of adult kidney\u2010only transplant recipients between October 2009 and December 2012 was performed to examine outcomes between patients with (n\u00a0=\u00a0111) and without (n\u00a0=\u00a098) severe preoperative <jats:styled-content style=\"fixed-case\">HTN<\/jats:styled-content> defined as <jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content> &gt;180 or <jats:styled-content style=\"fixed-case\">DBP<\/jats:styled-content>&gt; 110\u00a0mmHg.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Recipients with severe <jats:styled-content style=\"fixed-case\">HTN<\/jats:styled-content> were older (56.7\u00a0\u00b1\u00a013.0 vs. 53.5\u00a0\u00b1\u00a012.4\u00a0yr, p\u00a0=\u00a00.07) and significantly more likely to receive an expanded criteria donor kidney (32.7% vs. 12.2%, p\u00a0=\u00a00.02). No patients developed hypertensive crisis, intracranial hemorrhage, or life threatening ventricular arrhythmias within 30\u00a0d post\u2010transplantation; however, three patients with severe <jats:styled-content style=\"fixed-case\">HTN<\/jats:styled-content> had cardiac events: two with demand ischemia and one with decompensate heart failure. Two patients in the control group had decompensated heart failure. There were no differences between the groups in terms of cardiac event (2.7% vs. 2.0%, p\u00a0=\u00a00.75), one\u2010yr patient survival (98.2% vs. 98.0%, p\u00a0=\u00a00.90) or graft survival (90.1% vs. 92.9%, p\u00a0=\u00a00.48), nadir creatinine &gt;2\u00a0mg\/dL (4.6% vs. 6.2%, p\u00a0=\u00a00.62), length of stay&gt;6\u00a0d (37.8% vs. 35.7%, p\u00a0=\u00a00.75), and <jats:styled-content style=\"fixed-case\">DGF<\/jats:styled-content> (52.3% vs. 63.3%, p\u00a0=\u00a00.11).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that severe preoperative HTN should not be considered an absolute contraindication to kidney transplant in patients who are otherwise clinically stable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12579","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T08:43:12Z","timestamp":1434616992000},"page":"781-785","source":"Crossref","is-referenced-by-count":1,"title":["Kidney 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Center Albert Einstein College of Medicine Bronx NY USA"},{"name":"Renal Division Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjali","family":"Gupta","sequence":"additional","affiliation":[{"name":"Montefiore\u2013Einstein Center for Transplantation Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"},{"name":"Renal Division Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Dunn","sequence":"additional","affiliation":[{"name":"Department of Surgery Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"de Boccardo","sequence":"additional","affiliation":[{"name":"Montefiore\u2013Einstein Center for Transplantation Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"},{"name":"Renal Division Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enver","family":"Akalin","sequence":"additional","affiliation":[{"name":"Montefiore\u2013Einstein Center for Transplantation Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"},{"name":"Renal Division Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liise","family":"Kayler","sequence":"additional","affiliation":[{"name":"Montefiore\u2013Einstein Center for Transplantation Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA"},{"name":"Department of Surgery Montefiore Medical Center Albert Einstein College of Medicine Bronx NY 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