{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:10:39Z","timestamp":1758636639922,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,11,3]],"date-time":"2015-11-03T00:00:00Z","timestamp":1446508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2015,12]]},"abstract":"Abstract<\/jats:title>The kidney allocation system (KAS<\/jats:styled-content>) aims to improve deceased donor kidney transplant outcomes by matching of donor allografts and kidney recipients using the kidney donor risk index (KDRI<\/jats:styled-content>) and recipient estimated post\u2010transplant survival (EPTS<\/jats:styled-content>) indices. In this single\u2010center study, KAS<\/jats:styled-content> was retroactively applied to 573 adult deceased donor kidney transplants (2004\u20132012) performed in the extended criteria\/standard criteria donor (ECD<\/jats:styled-content>\/SCD<\/jats:styled-content>) era. Donor KDRI<\/jats:styled-content> and recipient EPTS<\/jats:styled-content> were calculated, and transplants were analyzed to identify KAS<\/jats:styled-content> fits. These were defined as allocation of top 20% allografts to top 20% recipients and bottom 80% allografts to bottom 80% recipients. On retroactive calculation, 70.2% of all transplants fit the KAS<\/jats:styled-content>. Transplants that fit the KAS<\/jats:styled-content> had inferior 1\u2010 and 5\u2010yr patient survival (95.5% vs. 98.8%, p = 0.048, and 83.4% vs. 91.7%, p = 0.018) and similar 1\u2010 and 5\u2010yr graft survival compared to transplants that did not fit the KAS<\/jats:styled-content> (91.3% vs. 94.1%, p = 0.276, and 72.7% vs. 73.9%, p = 0.561). While EPTS<\/jats:styled-content> correlated with recipient survival (HR<\/jats:styled-content> = 2.96, p < 0.001), KDRI<\/jats:styled-content> correlated with both recipient (HR<\/jats:styled-content> = 3.56, p < 0.001) and graft survival (HR<\/jats:styled-content> = 3.23, p < 0.001). Overall, retroactive application of the KAS<\/jats:styled-content> to transplants performed in the ECD<\/jats:styled-content>\/SCD<\/jats:styled-content> era did not identify superior patient survival for kidneys allocated in accordance with the KAS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/ctr.12642","type":"journal-article","created":{"date-parts":[[2015,10,5]],"date-time":"2015-10-05T15:32:39Z","timestamp":1444059159000},"page":"1148-1155","source":"Crossref","is-referenced-by-count":2,"title":["Retroactive application of the new kidney allocation system to renal transplants performed in the ECD<\/scp>\/SCD<\/scp> era"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8157-1598","authenticated-orcid":false,"given":"Rajesh","family":"Ramanathan","sequence":"first","affiliation":[{"name":"Hume\u2010Lee Transplant Center Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Gupta","sequence":"additional","affiliation":[{"name":"Hume\u2010Lee Transplant Center Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joohyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Hume\u2010Lee Transplant Center Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keri","family":"Quinn","sequence":"additional","affiliation":[{"name":"Hume\u2010Lee Transplant Center Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Behnke","sequence":"additional","affiliation":[{"name":"Hume\u2010Lee Transplant Center Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Sharma","sequence":"additional","affiliation":[{"name":"Hume\u2010Lee Transplant Center Virginia Commonwealth University Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,11,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04146.x"},{"key":"e_1_2_5_3_1","unstructured":"United States Organ Transplantation.OPTN & SRTR Annual Data Report 2011. U.S. Department of Health and Human Services 2012(December)."},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12135"},{"key":"e_1_2_5_5_1","unstructured":"Organ Procurement and Transplantation Network (OPTN). OPTN policies. Available at:http:\/\/optn.transplant.hrsa.gov\/media\/1200\/optn_policies.pdf#nameddest=Policy_08. 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