{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:53:25Z","timestamp":1777643605364,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T00:00:00Z","timestamp":1453939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this work was to investigate the\u00a0association of vertebral and peripheral fractures 10\u00a0yr after grafting with bone metabolic markers and body mass density (<jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>One hundred thirty\u2010eight recipients with stable graft function were included in a cross\u2010sectional study. Graft function, biochemical mineral metabolism markers and body mass density (<jats:styled-content style=\"fixed-case\">DEXA<\/jats:styled-content>) were measured. Vertebral fractures were assessed by a semiquantitative analysis of lateral spine X\u2010ray exam.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At the time of the study, intact parathyroid hormone levels were 127.5\u00a0\u00b1\u00a078.4\u00a0pg\/mL and serum calcidiol 20.4\u00a0\u00b1\u00a09.3\u00a0ng\/mL. <jats:styled-content style=\"fixed-case\">DEXA<\/jats:styled-content> showed osteopenia in 47% and osteoporosis in 23% at lumbar spine, 51% and 14% at femoral neck, and 53% and 8% at trochanter. Eighty\u2010five recipients presented vertebral fractures, 69 mild and 16 moderate\/severe fractures. In the multivariate analysis, vertebral fractures were associated with older age (p\u00a0=\u00a00.010), length of follow\u2010up (p\u00a0=\u00a00.022) and trochanter T\u2010score (p\u00a0=\u00a00.038). Twenty\u2010three patients presented peripheral fractures and 19 of them also had vertebral fractures. Patients with peripheral fractures were younger, mostly women and had lower <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Vertebral fractures were associated with lower <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> at trochanter. Most fractures were mild and were several times more frequent than in general population. Their clinical significance needs to be determined.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12666","type":"journal-article","created":{"date-parts":[[2015,11,7]],"date-time":"2015-11-07T07:24:10Z","timestamp":1446881050000},"page":"131-137","source":"Crossref","is-referenced-by-count":8,"title":["Bone fractures and lumbar mineral density after renal transplantation. 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