{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T18:18:40Z","timestamp":1763057920826},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,1,30]],"date-time":"2016-01-30T00:00:00Z","timestamp":1454112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to determine whether patients with end\u2010stage kidney disease (<jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content>) on hemodialysis (<jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>) undergoing kidney transplant evaluation are at higher risk for colonic neoplasia than the general population. This is a retrospective cohort study of patients with <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> who underwent a first screening colonoscopy while undergoing kidney transplant evaluation. Data were collected on the prevalence of adenomatous polyps and advanced adenomas in 70 patients with <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> and 70 controls, undergoing their first screening colonoscopy, matched for age, gender, and endoscopist. At the time of the colonoscopy, an average time on <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> was 3.2 \u00b1 2.9 yr. The prevalence of adenomatous polyps was significantly higher in <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> (54.3% vs. 32.9%, p = 0.008) than in controls. In a multivariate analysis controlling for other factors, <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> remained a risk factor for the presence of adenomas (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.06, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.21, 7.73). No colonoscopy\u2010related complications were reported in the patients with <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>. We demonstrate a significantly higher prevalence of adenomatous polyps in patients with <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> undergoing a first screening colonoscopy as part of kidney transplant evaluation. In addition, colonoscopy can be safely performed in this population.<\/jats:p>","DOI":"10.1111\/ctr.12684","type":"journal-article","created":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T10:28:48Z","timestamp":1451471328000},"page":"256-262","source":"Crossref","is-referenced-by-count":13,"title":["High prevalence of colon adenomas in end\u2010stage kidney disease patients on hemodialysis undergoing renal transplant evaluation"],"prefix":"10.1111","volume":"30","author":[{"given":"Monica","family":"Saumoy","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Weill Cornell Medical College New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun B.","family":"Jesudian","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Weill Cornell Medical College New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Aden","sequence":"additional","affiliation":[{"name":"Department of Public Health Weill Cornell Medical College New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Serur","sequence":"additional","affiliation":[{"name":"Department of Nephrology Weill Cornell Medical College New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subha","family":"Sundararajan","sequence":"additional","affiliation":[{"name":"Riverview Medical Center Red Bank Gastroenterology Red Bank NJ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geethan","family":"Sivananthan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Lenox Hill Hospital New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Gambarin\u2010Gelwan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Memorial Sloan Kettering Cancer Center New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,30]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"United States Cancer Statistics: 1999\u20132009 Incidence and Mortality Web\u2010based Report","author":"U.S. Cancer Statistics Working Group","year":"2013"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.06.001"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199312303292701"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1100370"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.23.2823"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01908.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e4657"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-007-0084-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0674-0"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.09.029"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-011-1400-8"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(05)00152-7"},{"key":"e_1_2_8_14_1","unstructured":"SivananthanG SundararajanS AdenBet al.High prevalence of colonic adenoma in the patients with end\u2010stage renal disease (ESRD) on hemodialysis undergoing renal transplant evaluation. 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