{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T19:11:53Z","timestamp":1767899513923,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,3,17]],"date-time":"2016-03-17T00:00:00Z","timestamp":1458172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>With the worldwide shortage of donor organs, use of ventricular assist device (<jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content>) therapy is rapidly increasing in both the bridge to transplant and destination therapy settings. However, the high cost of <jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content>s and <jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content> care is a cause for concern for policy makers who have relied on the limited supply of donor hearts to naturally cap health expenditure on heart transplantation (<jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>x). We sought to compare costs of the first 12 months of care of <jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content>s vs. <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>x. Single center retrospective study utilizing real generated costs over a three yr span from 2010\u20132012. Only patients with 12 months of costing data were included. Costs of 28 <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>x patients and 24 <jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content> patients were analyzed. Index admission costs were more than double in the <jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content> group compared to the <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>x group and this was driven by the procurement costs and length of stay which increased almost all aspects of in hospital care costs. Subsequent costs were six times higher in the <jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>x group and this was driven largely by pharmaceuticals. <jats:styled-content style=\"fixed-case\">VAD<\/jats:styled-content> therapy remains a very expensive treatment option for end stage heart failure patients. Device prices need to reduce substantially to make this a more widely applicable and cost effective treatment option.<\/jats:p>","DOI":"10.1111\/ctr.12725","type":"journal-article","created":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T03:16:48Z","timestamp":1456456608000},"page":"598-605","source":"Crossref","is-referenced-by-count":21,"title":["Cost comparison of heart transplant vs. left ventricular assist device therapy at one year"],"prefix":"10.1111","volume":"30","author":[{"given":"Silvana F.","family":"Marasco","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery The Alfred Hospital Prahran Melbourne Vic. Australia"},{"name":"Department of Surgery Monash University Melbourne Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robyn","family":"Summerhayes","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery The Alfred Hospital Prahran Melbourne Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Quayle","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery The Alfred Hospital Prahran Melbourne Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"McGiffin","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery The Alfred Hospital Prahran Melbourne Vic. Australia"},{"name":"Department of Surgery Monash University Melbourne Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Luthe","sequence":"additional","affiliation":[{"name":"Finance Department The Alfred Hospital Prahran Melbourne Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.09.052"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2014.11.004"},{"key":"e_1_2_7_4_1","unstructured":"International Society of Heart and Lung Transplantation website.https:\/\/www.ishlt.org\/registries."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12496"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.14503\/THIJ-14-4855"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12440"},{"key":"e_1_2_7_8_1","unstructured":"Australian National Blood Authority.www.blood.gov.au\/national-product-list."},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12577"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.01.062"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2014.11.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2011.01292.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000194"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.113.000807"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1405158"},{"key":"e_1_2_7_16_1","unstructured":"World Health Organisation.Cost\u2010effectiveness thresholds.http:\/\/www.who.int\/choice\/costs\/CER_thresholds\/en\/index.html."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2010.10.016"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.01.111"},{"key":"e_1_2_7_19_1","first-page":"439","article-title":"The cost\u2010utility of left ventricular assist devices for end\u2010stage heart failure patients ineligible for cardiac transplantation: a systematic review and critical appraisal of economic evaluations","volume":"3","author":"Neyt M","year":"2014","journal-title":"Ann Cardiothorac Surg"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.139824"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12725","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12725","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:20:43Z","timestamp":1695514843000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,17]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/ctr.12725"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12725","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,17]]}}}