{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T01:14:04Z","timestamp":1778721244674,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We aimed to examine the clinical outcomes of sensitized pregnant kidney transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of female patients who received kidney transplant at Montefiore transplant center between June 1, 2009 through December 31, 2014 and had a documented pregnancy in our system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that 11 women had pregnancies during this period with a median age of 36 yr (range 22, 39). Pregnancies occurred at a median of 3.1 yr (1.1, 8.7) after transplantation. Pre\u2010pregnancy patients\u2019 median serum creatinine levels and spot urine protein\/creatinine ratio were 1.1 mg\/dL (1.1, 2.1) and 0.55 g\/d (0, 1.2), respectively. Eight patients were sensitized with panel reactive antibody (<jats:styled-content style=\"fixed-case\">PRA<\/jats:styled-content>) levels &gt; 0% and three had <jats:styled-content style=\"fixed-case\">PRA<\/jats:styled-content> of 0%. The sensitized group had a higher incidence of adverse pregnancy outcomes; one stillbirth and two second trimester miscarriage. During a median follow\u2010up of 2.3 yr (1.2, 4) after delivery, three high <jats:styled-content style=\"fixed-case\">PRA<\/jats:styled-content> patients (37%) developed antibody\u2010mediated rejection that led to graft loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We observed an increased risk of rejection, graft loss, and adverse pregnancy outcomes in sensitized kidney recipients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12751","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T18:46:11Z","timestamp":1461264371000},"page":"791-795","source":"Crossref","is-referenced-by-count":21,"title":["Pregnancy in sensitized kidney transplant recipients: a single\u2010center experience"],"prefix":"10.1111","volume":"30","author":[{"given":"Maria","family":"Ajaimy","sequence":"first","affiliation":[{"name":"Montefiore \u2013 Einstein Center for Transplantation Albert Einstein College of Medicine Bronx NY USA"},{"name":"Division of Nephrology Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Lubetzky","sequence":"additional","affiliation":[{"name":"Montefiore \u2013 Einstein Center for Transplantation Albert Einstein College of Medicine Bronx NY USA"},{"name":"Division of Nephrology Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Jones","sequence":"additional","affiliation":[{"name":"Montefiore \u2013 Einstein Center for Transplantation Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Layla","family":"Kamal","sequence":"additional","affiliation":[{"name":"Montefiore \u2013 Einstein Center for Transplantation Albert Einstein College of Medicine Bronx NY USA"},{"name":"Division of Nephrology Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Colovai","sequence":"additional","affiliation":[{"name":"Transplant Immunology Laboratory Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"de Boccardo","sequence":"additional","affiliation":[{"name":"Montefiore \u2013 Einstein Center for Transplantation Albert Einstein College of Medicine Bronx NY USA"},{"name":"Division of Nephrology Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enver","family":"Akalin","sequence":"additional","affiliation":[{"name":"Montefiore \u2013 Einstein Center for Transplantation Albert Einstein College of Medicine Bronx NY USA"},{"name":"Division of Nephrology Albert Einstein College of Medicine Bronx NY 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