{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:44:22Z","timestamp":1768005862252,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T00:00:00Z","timestamp":1466985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000102","name":"Health Resources and Services Administration","doi-asserted-by":"crossref","award":["234-2005-370011C"],"award-info":[{"award-number":["234-2005-370011C"]}],"id":[{"id":"10.13039\/100000102","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Concern over transmission of viral infections has been reported to result in higher discard rates of high infectious risk kidneys (HIR) although data on actual viral transmission rates are lacking. At our center, we performed 89 HIR and 533 non\u2010HIR kidney transplants (KTs) between 2004 and 2011. Follow\u2010up screening labs in recipients of HIR kidneys tested for human immunodeficiency virus, hepatitis C virus, and hepatitis B virus did not reveal any cases of viral transmission over median follow\u2010up of 4.3\u00a0years. Patient and graft outcomes were similar at 5\u00a0years between HIR and non\u2010HIR KTs. An updated analysis of the Organ Procurement and Transplant Network (OPTN) registry of deceased\u2010donor kidney transplants between 2008 and 2012 included 57\u00a0526 transplants was performed. Retrospective calculation of KDRI (kidney donor risk index) differed (<jats:italic>P<\/jats:italic>&lt;.001) between all groups with median KDRI of 0.99 for HIR kidneys, 1.07 for non\u2010HIR standard criteria donor kidneys, and 1.81 for non\u2010HIR expanded criteria donor (ECD) kidneys. This was reflected in the significantly improved 5\u2010year graft survival for HIR KTs when compared with non\u2010HIR ECD KTs (84% vs 78%; <jats:italic>P<\/jats:italic>&lt;.001). Our data can guide counseling of KT candidates about the safety and benefits of HIR kidneys.<\/jats:p>","DOI":"10.1111\/ctr.12761","type":"journal-article","created":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T07:45:19Z","timestamp":1462434319000},"page":"886-893","source":"Crossref","is-referenced-by-count":17,"title":["Outcomes of kidney transplants and risk of infection transmission from increased infectious risk donors"],"prefix":"10.1111","volume":"30","author":[{"given":"Ashley J.","family":"Limkemann","sequence":"first","affiliation":[{"name":"Department of Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Wolfe","sequence":"additional","affiliation":[{"name":"Department of Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Sharma","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne L.","family":"King","sequence":"additional","affiliation":[{"name":"Division of Nephrology Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Behnke","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mili Jay","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Nephrology Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc P.","family":"Posner","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian H.","family":"Cotterell","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandra S.","family":"Bhati","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankur","family":"Gupta","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhiren","family":"Kumar","sequence":"additional","affiliation":[{"name":"Division of Nephrology Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Gupta","sequence":"additional","affiliation":[{"name":"Division of Nephrology Virginia Commonwealth University  Richmond VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912023412303"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31829807d1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31828a9493"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.3.s4.11.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.12659\/AOT.883845"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01769.x"},{"key":"e_1_2_8_8_1","first-page":"1","article-title":"Guidelines for preventing transmission of human immunodeficiency virus through transplantation of human tissue and organs. 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