{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:20:27Z","timestamp":1790662827083,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T00:00:00Z","timestamp":1466553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this retrospective, single\u2010center data analysis, we audited our clinical practice to treat <jats:italic>Stenotrophomonas maltophilia<\/jats:italic> in asymptomatic lung transplant recipients (LTRs). Eighteen LTRs with confirmed isolation of <jats:italic>S.\u00a0maltophilia<\/jats:italic> were identified. Twelve of these LTRs have been treated with antibiotics, while 6 were managed without treatment. Treatment was based on antibiograms (trimethoprim\/sulfamethoxazole [TMP\/SMX] (8\/12), levofloxacin (1\/12), or both (3\/12). Clearance (12\/12 vs 6\/6), eradication (10\/12 vs 3\/6, <jats:italic>P<\/jats:italic>=.27), and freedom from <jats:italic>S.\u00a0maltophilia<\/jats:italic> recurrence (83%\u00b111% vs 40%\u00b122% after one year, log\u2010rank <jats:italic>P<\/jats:italic>=.09) were not found to differ significantly between treated and untreated patients. None of the patient groups showed significant changes in lung function or biochemical variables. Creatinine levels at the end of the study period were found to be higher in treated patients compared to the untreated group (<jats:italic>P<\/jats:italic>=.049). De novo acquired TMP\/SMX resistance in <jats:italic>S.\u00a0maltophilia<\/jats:italic> strains was not observed. These results indicate no evidence that antibiotic treatment for <jats:italic>S.\u00a0maltophilia<\/jats:italic> in asymptomatic LTRs alters lung function or the clinical outcome.<\/jats:p>","DOI":"10.1111\/ctr.12770","type":"journal-article","created":{"date-parts":[[2016,5,25]],"date-time":"2016-05-25T00:54:10Z","timestamp":1464137650000},"page":"857-863","source":"Crossref","is-referenced-by-count":10,"title":["Isolation of <i>Stenotrophomonas maltophilia<\/i> in asymptomatic lung transplant recipients: effects of treatment on eradication and outcome"],"prefix":"10.1111","volume":"30","author":[{"given":"Patrick","family":"Hofmann","sequence":"first","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hombach","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology University\u00a0Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhardt","family":"Seifert","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Biostatistics and Prevention University Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mac\u00e9 M.","family":"Schuurmans","sequence":"additional","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"B\u00fcrgi","sequence":"additional","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Isenring","sequence":"additional","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas J.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Hospital Epidemiology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Kohler","sequence":"additional","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Benden","sequence":"additional","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars C.","family":"Huber","sequence":"additional","affiliation":[{"name":"Division of Pulmonology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-43-3-606"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/587180"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.5.1140"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1304.061378"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201010-1668ED"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201009-1392OC"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2003.017707"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70419-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13665-014-0079-z"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000339345"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12228"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-200832"},{"key":"e_1_2_6_14_1","unstructured":"IBM Corp. Released 2013. IBM SPSS Statistics for Windows Version 22.0.Armonk NY:IBM Corp."},{"key":"e_1_2_6_15_1","first-page":"11","article-title":"A prospective, randomized, double\u2010blind study of trimethoprim\u2010sulfamethoxazole for prophylaxis of infection in renal transplantation. Side effects of trimethoprim\u2010sulfamethoxazole, interaction with cyclosporine","volume":"119","author":"Maki DG","year":"1992","journal-title":"J Lab Clin Med"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.058271"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04800908"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12770","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T16:22:04Z","timestamp":1696350124000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,22]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1111\/ctr.12770"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12770","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,22]]}}}