{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:43:38Z","timestamp":1770295418921,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Living kidney donor evaluation commonly includes nuclear renography to assess split kidney function and computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) scan to evaluate anatomy. To streamline donor workup and minimize exposure to radioisotopes, we sought to assess the feasibility of using proportional kidney volume from <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> volumetry in lieu of nuclear renography. We examined the correlation between techniques and assessed their ability to predict residual postoperative kidney function following live donor nephrectomy. In a cohort of 224 live kidney donors, we compared proportional kidney volume derived by <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> volumetry with split kidney function derived from nuclear renography and found only modest correlation (left kidney <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>=26.2%, right kidney <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>=26.7%). In a subset of 88 live kidney donors with serum creatinine measured 6\u00a0months postoperatively, we compared observed estimated glomerular filtration rate (<jats:styled-content style=\"fixed-case\">eGFR<\/jats:styled-content>) at 6\u00a0months with predicted <jats:styled-content style=\"fixed-case\">eGFR<\/jats:styled-content> from preoperative imaging. Compared to nuclear renography, <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> volumetry more closely approximated actual observed postoperative <jats:styled-content style=\"fixed-case\">eGFR<\/jats:styled-content> for Chronic Kidney Disease Epidemiology Collaboration (<jats:italic>J<\/jats:italic>\u2010test: <jats:italic>P<\/jats:italic>=.02, Cox\u2013Pesaran test: <jats:italic>P<\/jats:italic>=.01) and Mayo formulas (<jats:italic>J<\/jats:italic>\u2010test: <jats:italic>P<\/jats:italic>=.004, Cox\u2013Pesaran test: <jats:italic>P<\/jats:italic>&lt;.001). These observations support the use of <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> volumetry for estimation of split kidney function in healthy individuals with normal kidney function and morphology.<\/jats:p>","DOI":"10.1111\/ctr.12784","type":"journal-article","created":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T08:25:45Z","timestamp":1468225545000},"page":"1028-1035","source":"Crossref","is-referenced-by-count":34,"title":["<scp>CT<\/scp> volumetry is superior to nuclear renography for prediction of residual kidney function in living donors"],"prefix":"10.1111","volume":"30","author":[{"given":"Andrew S.","family":"Barbas","sequence":"first","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"},{"name":"Division of General Surgery University Health Network Toronto Canada"},{"name":"Department of Surgery University of Toronto Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Li","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murtuza","family":"Zair","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A.","family":"Van","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olusegun","family":"Famure","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J.","family":"Dib","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"},{"name":"Division of General Surgery University Health Network Toronto Canada"},{"name":"Department of Surgery University of Toronto Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome M.","family":"Laurence","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"},{"name":"Division of General Surgery University Health Network Toronto Canada"},{"name":"Department of Surgery University of Toronto Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Joseph","family":"Kim","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"},{"name":"Division of Nephrology University Health Network Toronto Canada"},{"name":"Department of Medicine University of Toronto Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Ghanekar","sequence":"additional","affiliation":[{"name":"Kidney Transplant Program Toronto General Hospital University Health Network Toronto Canada"},{"name":"Division of General Surgery University Health Network Toronto Canada"},{"name":"Department of Surgery University of Toronto Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12365"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000099784.52825.8e"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.05.117"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12195"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2521081873"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00030110"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.11.013"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-010-0349-y"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841850410005282"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0284185113504195"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e318251db15"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-009-9595-7"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.4023"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-200102000-00007"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2006.06.110"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.12080"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12112338"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000889"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2014.11.044"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-6-199903160-00002"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-12-200412210-00009"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2003.09.026"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000918"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.12784","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.12784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T03:37:51Z","timestamp":1696304271000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.12784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,11]]},"references-count":24,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/ctr.12784"],"URL":"https:\/\/doi.org\/10.1111\/ctr.12784","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,11]]}}}