{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:31:42Z","timestamp":1792276302387,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,9,24]],"date-time":"2016-09-24T00:00:00Z","timestamp":1474675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lecithin cholesterol acyl transferase (<jats:styled-content style=\"fixed-case\">LCAT<\/jats:styled-content>) deficiency is a rare autosomal recessive disorder of lipoprotein metabolism that results in end\u2010stage renal disease (<jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content>) necessitating transplantation. As <jats:styled-content style=\"fixed-case\">LCAT<\/jats:styled-content> is produced in the liver, combined kidney and liver transplantation was proposed to cure the clinical syndrome of <jats:styled-content style=\"fixed-case\">LCAT<\/jats:styled-content> deficiency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 29\u2010year\u2010old male with <jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content> secondary to <jats:styled-content style=\"fixed-case\">LCAT<\/jats:styled-content> deficiency underwent a sequential kidney\u2013liver transplantation from the same living donor (LD). One\u00a0year following the kidney transplant, auxiliary partial orthotopic liver transplant (<jats:styled-content style=\"fixed-case\">APOLT<\/jats:styled-content>) of a left lateral segment from the same donor was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 5\u00a0years follow\u2010up, there have been no major complications, readmissions, or rejection episodes. Serum lipid abnormalities recurred within the first year, but liver and kidney allograft function remains intact.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Few cases of sequential transplantation from the same LD have been performed in adults. This is the first <jats:styled-content style=\"fixed-case\">APOLT<\/jats:styled-content> and multi\u2010organ transplant performed for <jats:styled-content style=\"fixed-case\">LCAT<\/jats:styled-content> deficiency. Sequential organ transplant from the same LD for <jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content> secondary to a metabolic disorder of the liver is feasible in adults and should be further investigated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.12826","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T14:44:09Z","timestamp":1470321849000},"page":"1370-1374","source":"Crossref","is-referenced-by-count":11,"title":["Sequential kidney\u2013liver transplantation from the same living donor for lecithin cholesterol acyl transferase deficiency"],"prefix":"10.1111","volume":"30","author":[{"given":"Sarwat B.","family":"Ahmad","sequence":"first","affiliation":[{"name":"Department of Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of 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