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One year after transplantation, we examined 150 patients for post\u2010transplant diabetes performing oral glucose tolerance tests and body composition measurements including visceral adipose tissue (<jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content>) content from dual\u2010energy X\u2010ray absorptiometry scans. We found that glucose metabolism was generally improved over the first year post\u2010transplant, and that the levels of <jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content> and percentage <jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content> of total body fat mass (<jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content><jats:sub>%tot<\/jats:sub><jats:styled-content style=\"fixed-case\"><jats:sub>BFM<\/jats:sub><\/jats:styled-content>) were lowest in those with normal glucose tolerance and highest in those with post\u2010transplant diabetes mellitus. In a multivariable linear regression analysis, 87.4% of the variability in fasting glucose concentration was explained by insulin resistance (<jats:italic>P<\/jats:italic>&lt;.001, <jats:styled-content style=\"fixed-case\">HOMA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IR<\/jats:styled-content> index), beta cell function (<jats:italic>P<\/jats:italic>&lt;.001, <jats:styled-content style=\"fixed-case\">HOMA<\/jats:styled-content>\u2010beta), <jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content><jats:sub>%tot<\/jats:sub><jats:styled-content style=\"fixed-case\"><jats:sub>BFM<\/jats:sub><\/jats:styled-content> (<jats:italic>P<\/jats:italic>=.007), and body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>;<jats:italic> P<\/jats:italic>=.015; total model <jats:italic>P<\/jats:italic>&lt;.001), while insulin resistance (<jats:italic>P<\/jats:italic>&lt;.001) and beta cell function (<jats:italic>P<\/jats:italic>&lt;.001) explained 31.9% of the variability in 2\u2010hour glucose concentration in a multivariable model (total model <jats:italic>P<\/jats:italic>&lt;.001). <jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content> was associated with glucose metabolism to a larger degree than <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>. In conclusion, <jats:styled-content style=\"fixed-case\">VAT<\/jats:styled-content> is associated with hyperglycemia one year after kidney transplantation, and insulin resistance and beta cell function estimates are the most robust markers of glucose metabolism.<\/jats:p>","DOI":"10.1111\/ctr.12869","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T19:38:32Z","timestamp":1479325112000},"source":"Crossref","is-referenced-by-count":18,"title":["Visceral fat is strongly associated with post\u2010transplant diabetes mellitus and glucose metabolism 1\u00a0year after kidney transplantation"],"prefix":"10.1111","volume":"31","author":[{"given":"Marit Elizabeth","family":"von D\u00fcring","sequence":"first","affiliation":[{"name":"Section of Nephrology Department of Transplantation Medicine Oslo University Hospital, Rikshospitalet  Oslo Norway"},{"name":"Institute of Clinical Medicine Faculty of Medicine University of Oslo  Oslo 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