{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T09:13:42Z","timestamp":1769159622273,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,29]],"date-time":"2017-01-29T00:00:00Z","timestamp":1485648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Virginia Lee Cook Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Since the institution of the new kidney allocation system in December 2014, kidney transplant candidates with the highest calculated panel reactive antibodies (<jats:styled-content style=\"fixed-case\">cPRA<\/jats:styled-content>) of 99\u2010100 have been transplanted at much higher rates. However, concerns have been raised that outcomes in these patients might be impaired due to higher immunological risk and longer cold ischemia times resulting from long\u2010distance sharing of kidneys. Here, we compare outcomes at the University of Wisconsin between study patients with<jats:styled-content style=\"fixed-case\">cPRA<\/jats:styled-content>99\u2010100 and all other recipients of deceased donor kidneys transplanted between 12\/04\/2014 and 12\/31\/2015. All patients had at least 6\u00a0months post\u2010transplant follow\u2010up. The mean follow\u2010up was 13.9\u00b13\u00a0months in<jats:styled-content style=\"fixed-case\">cPRA<\/jats:styled-content>\u226599% and 12.3\u00b13.5\u00a0months in<jats:styled-content style=\"fixed-case\">cPRA<\/jats:styled-content>\u226498%. There was a total of 152 transplants, 25 study patients, and 127 controls. No statistically significant differences were found between the two groups in delayed graft function, rejection, kidney function, graft and patient survival, or infections. We conclude that transplanting the most highly sensitized patients with kidneys shared outside their local donation service areas is associated with excellent short\u2010term outcomes that are comparable to controls.<\/jats:p>","DOI":"10.1111\/ctr.12895","type":"journal-article","created":{"date-parts":[[2016,12,18]],"date-time":"2016-12-18T04:52:56Z","timestamp":1482036776000},"source":"Crossref","is-referenced-by-count":13,"title":["Outcomes in the highest panel reactive antibody recipients of deceased donor kidneys under the new kidney allocation system"],"prefix":"10.1111","volume":"31","author":[{"given":"Sandesh","family":"Parajuli","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert R.","family":"Redfield","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery University of Wisconsin Hospital and Clinics Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad C.","family":"Astor","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI USA"},{"name":"Department of Population Health Sciences University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjang","family":"Djamali","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dixon B.","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery University of Wisconsin Hospital and Clinics Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier A.","family":"Mandelbrot","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,29]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"UNOS.Transplant Trends;2016.https:\/\/www.unos.org\/data\/transplant-trends\/#waitlists_by_organ+state+AllStates. 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