{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:38Z","timestamp":1787014058716,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,6,11]],"date-time":"2017-06-11T00:00:00Z","timestamp":1497139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI 14\/01055"],"award-info":[{"award-number":["PI 14\/01055"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2017,7]]},"abstract":"Abstract<\/jats:title>\n \n Liver transplantation (\n LT<\/jats:styled-content>\n ) is indicated in autoimmune hepatitis (\n AIH<\/jats:styled-content>\n ) for both acute presentation with liver failure and end\u2010stage chronic liver disease. Few studies have suggested an association between\n AIH<\/jats:styled-content>\n and coagulation disorders and a higher incidence of portal vein thrombosis (\n PVT<\/jats:styled-content>\n ) in patients with\n AIH<\/jats:styled-content>\n listed for\n LT<\/jats:styled-content>\n . The aim of this study was to determine the incidence of thrombotic complications, particularly\n PVT<\/jats:styled-content>\n , in a cohort of 37 patients undergoing\n LT<\/jats:styled-content>\n because of\n AIH<\/jats:styled-content>\n .\n PVT<\/jats:styled-content>\n was present before transplantation in 30% (n=11) of these patients compared to 11% in the whole population transplanted in our center (\n P<\/jats:italic>\n =.002). On comparing only patients with cirrhosis,\n PVT<\/jats:styled-content>\n was present in 55% of the\n AIH<\/jats:styled-content>\n group, being 12% in the whole cohort (\n P<\/jats:italic>\n <.001). Among patients with\n PVT<\/jats:styled-content>\n before\n LT<\/jats:styled-content>\n , no patient receiving anticoagulation therapy early after\n LT<\/jats:styled-content>\n developed recurrence of\n PVT<\/jats:styled-content>\n , whereas two patients (33%) without anticoagulation therapy did. The increased incidence of\n PVT<\/jats:styled-content>\n in the pretransplant period and the possibility of thrombosis recurrence after\n LT<\/jats:styled-content>\n suggest that patients with\n AIH<\/jats:styled-content>\n and\n PVT<\/jats:styled-content>\n could benefit from anticoagulation therapy after transplantation. However, further studies are needed to recommend anticoagulation in these patients in clinical practice.\n <\/jats:p>","DOI":"10.1111\/ctr.13001","type":"journal-article","created":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T10:06:51Z","timestamp":1494410811000},"source":"Crossref","is-referenced-by-count":13,"title":["Increased risk of portal vein thrombosis in patients with autoimmune hepatitis on the liver transplantation waiting list"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5810-8802","authenticated-orcid":false,"given":"Pablo","family":"Ruiz","sequence":"first","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Sastre","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Crespo","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annabel","family":"Blasi","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Colmenero","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Garc\u00eda\u2010Valdecasas","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miquel","family":"Navasa","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit Hospital Cl\u00ednic de Barcelona Institut d'Investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS) Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd) University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.03.005"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22018"},{"key":"e_1_2_8_4_1","first-page":"17","article-title":"Liver transplantation in the United States from 1987\u20101998: updated results from the Pitt\u2010UNOS Liver 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