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Pooled sensitivity, specificity, positive and negative likelihood ratios, hierarchical summary receiver operating characteristic (HSROC<\/jats:styled-content>) curves, and the area under the curve (AUC<\/jats:styled-content>) were estimated using HSROC<\/jats:styled-content> and bivariate random\u2010effects models.<\/jats:p><\/jats:sec>Results<\/jats:title>Twelve studies involving 1782 subjects were eligible for this meta\u2010analysis. For detecting significant HS<\/jats:styled-content> (>10%\u201030% steatosis in liver pathology) with CT<\/jats:styled-content> in liver donors, the pooled sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.81 (95% confidence interval [CI<\/jats:styled-content>]: 0.70\u20100.89), 0.94 (95% CI<\/jats:styled-content>: 0.90\u20100.96), 13.7 (95% CI<\/jats:styled-content>: 8.1\u201023.1), and 0.20 (95% CI<\/jats:styled-content>: 0.12\u20100.33). The AUC<\/jats:styled-content> was 0.95 (95% CI<\/jats:styled-content>: 0.92\u20100.96). For detecting the presence of HS<\/jats:styled-content>, these corresponding diagnostic estimates were 0.50 (95% CI<\/jats:styled-content>: 0.36\u20100.64), 0.90 (95% CI<\/jats:styled-content>: 0.83\u20100.95), 5.2 (95% CI<\/jats:styled-content>: 3.1\u20108.9), 0.55 (95% CI<\/jats:styled-content>: 0.42\u20100.72), and 0.80 (95% CI<\/jats:styled-content>: 0.76\u20100.83). Moderate\u2010to\u2010high heterogeneity was detected.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Computed tomography shows high accuracy in detecting significant HS<\/jats:styled-content> while poor accuracy in detecting the presence of HS<\/jats:styled-content> in liver donors. Donors estimated to have significant HS<\/jats:styled-content> by CT<\/jats:styled-content> may avoid unnecessary liver biopsy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.13013","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T10:29:13Z","timestamp":1495103353000},"source":"Crossref","is-referenced-by-count":16,"title":["Accuracy of computed tomography for detecting hepatic steatosis in donors for liver transplantation: A meta\u2010analysis"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9253-1834","authenticated-orcid":false,"given":"Danping","family":"Zheng","sequence":"first","affiliation":[{"name":"Organ Transplant Center The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology Guangzhou China"},{"name":"Guangdong Provincial International Cooperation Base of Science and Technology (Organ 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