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We hypothesized that an early echocardiographic evaluation in severe brain injury (performed within 12\u00a0hours from <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> admission) could allow the detection of potentially reversible left ventricular (<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>) abnormalities and thus the initiation of tailored treatment whose effects could be assessed at a second echocardiogram performed when brain death develops. We assessed this hypothesis in 49 patients with severe brain injury who were potential heart donors. A reduction in <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> ejection fraction (<jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content>) (&lt;55%) was present in five patients (10.2%): diffuse hypokinesia in three patients (6.1%), segmental wall motion abnormalities in two (4.1%). Two patients showed apical ballooning (normal <jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content>). The three patients with diffuse hypokinesia showed, at the echocardiogram performed 12\u00a0hours later, a complete recovery of wall motion and <jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content>. Among patients with apical ballooning, a complete resolution was observed in both patients. Two patients were considered potentially eligible for heart donation, resulting in 20% increase in donor retrieval rate. In serious encephalic lesions, potentially evolving toward brain death, echocardiography performed after <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> admission allowed the identification of <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> abnormalities, which could be specifically treated with complete resolution.<\/jats:p>","DOI":"10.1111\/ctr.13094","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T12:37:23Z","timestamp":1503578243000},"source":"Crossref","is-referenced-by-count":13,"title":["The utility of serial echocardiograms for organ procurement in brain death"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0131-4450","authenticated-orcid":false,"given":"Chiara","family":"Lazzeri","sequence":"first","affiliation":[{"name":"Intensive Care Unit and Regional ECMO Referral Centre Emergency Department Azienda Ospedaliero\u2010Universitaria Careggi  Florence 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