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By the 2\u2010week assessment post\u2010transplant, there were no deaths, graft failures, or acute cellular rejections (<jats:styled-content style=\"fixed-case\">ACR<\/jats:styled-content>s) <jats:styled-content style=\"fixed-case\">ISHLT<\/jats:styled-content> grade\u00a0\u2265\u00a02R. By the 1\u2010year assessment post\u2010transplant, there were 1 (6%) infectious death, no graft failures, 2 (12%) grade 2R <jats:styled-content style=\"fixed-case\">ACR<\/jats:styled-content>s, 6 (35%) asymptomatic cytomegalovirus (<jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>) infections, and 4 (25%) treated infections. Our study was the first to show that low\u2010dose basiliximab induction in heart transplant resulted in favorable efficacy and safety outcomes. Additionally, calcineurin inhibitor (<jats:styled-content style=\"fixed-case\">CNI<\/jats:styled-content>) initiation in a low\u2010risk population could be safely delayed using the strategy of modified low\u2010dose postoperative basiliximab. This strategy also appears to allow subsequent early corticosteroid wean, although with the concomitant maintenance of higher <jats:styled-content style=\"fixed-case\">CNI<\/jats:styled-content> levels and higher dosing of mycophenolate.<\/jats:p>","DOI":"10.1111\/ctr.13132","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T06:56:38Z","timestamp":1507532198000},"source":"Crossref","is-referenced-by-count":16,"title":["Low\u2010dose basiliximab induction therapy in heart transplantation"],"prefix":"10.1111","volume":"31","author":[{"given":"Veraprapas","family":"Kittipibul","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pakpoom","family":"Tantrachoti","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pat","family":"Ongcharit","sequence":"additional","affiliation":[{"name":"Cardiac Center King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aekarach","family":"Ariyachaipanich","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Excellent Center of Organ Transplantation King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarawut","family":"Siwamogsatham","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Cardiac Center King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supaporn","family":"Sritangsirikul","sequence":"additional","affiliation":[{"name":"Excellent Center of Organ Transplantation King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanokwan","family":"Thammanatsakul","sequence":"additional","affiliation":[{"name":"Excellent Center of Organ Transplantation King Chulalongkorn Memorial Hospital Thai Red Cross Society Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7090-9947","authenticated-orcid":false,"given":"Sarinya","family":"Puwanant","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Medicine Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Cardiac Center King Chulalongkorn Memorial Hospital 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