{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:33:39Z","timestamp":1790660019919,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,30]],"date-time":"2018-03-30T00:00:00Z","timestamp":1522368000000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010915","name":"American Society of Transplant Surgeons","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010915","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2018,3]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n \n Renal transplant outcomes result from a combination of factors. Traditionally, donor factors were summarized by classifying kidneys as extended criteria or standard criteria. In 2014, the nomenclature changed to describe donor factors with the kidney donor profile index (\n KDPI<\/jats:styled-content>\n ). We aim to evaluate the relationship between\n KDPI<\/jats:styled-content>\n and delayed graft function (DGF), and the impact\n KDPI<\/jats:styled-content>\n on transplant outcomes for both donor after cardiac death (\n DCD<\/jats:styled-content>\n ) and donor after brain death (\n DBD<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n An\n IRB<\/jats:styled-content>\n \u2010approved single\u2010center retrospective chart review was performed from January 1999 to July 2013. The patients were divided into six groups:\n DBD KDPI<\/jats:styled-content>\n \u226460,\n DBD KPDI<\/jats:styled-content>\n 61\u201084,\n DBD KDPI<\/jats:styled-content>\n \u226585,\n DCD KDPI<\/jats:styled-content>\n \u226460,\n DCD KPDI<\/jats:styled-content>\n 61\u201084, and\n DCD KDPI<\/jats:styled-content>\n \u226585. Rates of\n DGF<\/jats:styled-content>\n , patient survival, and graft survival were examined among groups.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 2161 kidney transplants were included.\n DGF<\/jats:styled-content>\n rates increased, and graft and patient survival decreased with increasing\n KDPI<\/jats:styled-content>\n (\n P<\/jats:italic>\n \u00a0<\u00a0.001).\n DCD<\/jats:styled-content>\n kidneys had higher\n DGF<\/jats:styled-content>\n rates than their\n DBD<\/jats:styled-content>\n counterparts (\n P<\/jats:italic>\n \u00a0<\u00a0.001). In\n DCD<\/jats:styled-content>\n kidneys, a higher\n KDPI<\/jats:styled-content>\n score did not significantly affect the\n DGF<\/jats:styled-content>\n rates (\n P<\/jats:italic>\n \u00a0>\u00a0.302). There was no significant difference in graft or patient survival in all\u2010comers when comparing\n DCD<\/jats:styled-content>\n and\n DBD<\/jats:styled-content>\n kidneys with equivalent\n KDPI<\/jats:styled-content>\n s (\n P<\/jats:italic>\n \u00a0>\u00a0.317). Patients with\n DGF<\/jats:styled-content>\n across all categories demonstrated worse graft half\u2010lives.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The\n KDPI<\/jats:styled-content>\n system is an accurate predictor of donor contributions to transplant outcomes. Recipients of\n DBD<\/jats:styled-content>\n kidneys experience an increase in the rate of\n DGF<\/jats:styled-content>\n as their\n KDPI<\/jats:styled-content>\n increases.\n DCD<\/jats:styled-content>\n kidneys have higher\n DGF<\/jats:styled-content>\n rates than their\n DBD<\/jats:styled-content>\n counterparts with similar\n KDPI<\/jats:styled-content>\n s. Patients with documented post\u2010transplant\n DGF<\/jats:styled-content>\n had between 3\u2010 and 5\u2010year shorter graft half\u2010lives when compared to recipients that did not experience\n DGF<\/jats:styled-content>\n . Initiatives to reduce the rate of\n DGF<\/jats:styled-content>\n could provide a significant impact on graft survival and result in a reduction in the number of patients requiring retransplant.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ctr.13190","type":"journal-article","created":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T07:54:27Z","timestamp":1514966067000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":125,"title":["The impact of kidney donor profile index on delayed graft function and transplant outcomes: A single\u2010center analysis"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0213-6940","authenticated-orcid":false,"given":"Tiffany J.","family":"Zens","sequence":"first","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan S.","family":"Danobeitia","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Leverson","sequence":"additional","affiliation":[{"name":"Division of Statistics Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Chlebeck","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Zitur","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert R.","family":"Redfield","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony M.","family":"D'Alessandro","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Odorico","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dixon B.","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Division of Transplantation Department of Surgery University of Wisconsin School of Medicine and Public Health University of Wisconsin Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12585"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfu304"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13769"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181ac620b"},{"key":"e_1_2_9_6_1","volume-title":"A Guide to Calculating and Interpreting the Kidney Donor Profile Index (KDPI)","author":"Network 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