{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T12:45:21Z","timestamp":1782737121167,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,10]],"date-time":"2018-02-10T00:00:00Z","timestamp":1518220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Full\u2010split liver transplantation (<jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content>) offers the possibility to expand the donor pool by utilization of one liver for two adults. The aim of our study was to analyze the long\u2010term outcome in a large series and its applicability in the recent transplant era.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective analysis of all full\u2010split <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content> from deceased donors (1999\u20102015). Additionally, the potential of full\u2010split <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content> was retrospectively analyzed in all whole organ <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content> recipients between 2006 and 2015 (after introduction of the <jats:styled-content style=\"fixed-case\">MELD<\/jats:styled-content> allocation).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We performed 44 full\u2010split <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content>, thereof 82% before introduction of the <jats:styled-content style=\"fixed-case\">MELD<\/jats:styled-content>\u2010based allocation system in Germany. Analysis showed highly selected recipients (median <jats:styled-content style=\"fixed-case\">MELD<\/jats:styled-content> score 8 points) and organ data (median donor age 30\u00a0years). 5\u2010 and 10\u2010year patient survival rates after full\u2010left and full\u2010right <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content> were 90.7%\/90.7% and 85.2%\/56.8% (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.301), corresponding graft survival rates were 80.5%\/80.5% in full\u2010left grafts and 73.7%\/36.8% in full\u2010right graft (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.198).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the past, in case of strict donor and recipient selection, full\u2010split <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content> was a feasible method with a good outcome. Due to introduction of the national waiting list with a patient\u2010oriented allocation based on the <jats:styled-content style=\"fixed-case\">MELD<\/jats:styled-content> score in 2006, full\u2010split <jats:styled-content style=\"fixed-case\">LTX<\/jats:styled-content> seems to be not any longer applicable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.13205","type":"journal-article","created":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T15:59:48Z","timestamp":1516291188000},"source":"Crossref","is-referenced-by-count":20,"title":["Long\u2010term follow\u2010up after full\u2010split liver transplantation and its applicability in the recent transplant era"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2921-7943","authenticated-orcid":false,"given":"Uta","family":"Herden","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery and Transplantation University Medical Centre Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery and Transplantation University Medical Centre Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Sterneck","sequence":"additional","affiliation":[{"name":"Outpatient Centre University Medical Centre Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enke","family":"Grabhorn","sequence":"additional","affiliation":[{"name":"Department of Paediatric Hepatology University Medical Centre Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjoern","family":"Nashan","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery and Transplantation University Medical Centre Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(00)90026-5"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.01.037"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200104000-00013"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2001.10413.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1080\/00015458.2000.12098571","article-title":"Modified splitting technique for liver transplantation in adult\u2010sized recipients. 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