{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:23:51Z","timestamp":1762867431247,"version":"3.41.2"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T00:00:00Z","timestamp":1529020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2018,7]]},"abstract":"Abstract<\/jats:title>There are limited data regarding the association of different levels of BK<\/jats:styled-content> viremia and BK<\/jats:styled-content> nephropathy (BKN<\/jats:styled-content>), and graft outcomes. We studied the BK<\/jats:styled-content> plasma PCR<\/jats:styled-content> levels of all kidney transplant recipients (KTR<\/jats:styled-content>) transplanted at our institution between 01\/01\/2006 and 06\/30\/2014. Patients were divided into groups based on their highest BK<\/jats:styled-content> plasma PCR<\/jats:styled-content> level within the first year following transplantation: undetectable, low (<1000\u00a0copies\/mL), moderate (1000\u201010\u00a0000\u00a0copies\/mL), high (>10\u00a0000\u2010100\u00a0000\u00a0copies\/mL), very high (>100\u00a0000\u00a0copies\/mL), and those that had biopsy\u2010proven BKN<\/jats:styled-content>. There were a total of 1146 KTR<\/jats:styled-content> during the study period: 813 with undetectable BK<\/jats:styled-content> levels and 333 with any detectable BK<\/jats:styled-content> level (87 with low, 79 with moderate, 88 with high, 34 with very high level BK<\/jats:styled-content>, and 45 that had BKN<\/jats:styled-content>). Compared to KTR<\/jats:styled-content> with an undetectable BK<\/jats:styled-content> level, incidence of mortality, graft failure, rejections,and infections were not significantly different for those with low, moderate, high, or very high BK<\/jats:styled-content> level. Patients with BKN<\/jats:styled-content> had a higher rate of infection and higher rates of total graft failure or death\u2010censored graft failure compared to those with undetectable BK<\/jats:styled-content> levels. BK<\/jats:styled-content> viremia in the absence of BKN<\/jats:styled-content> does not significantly increase the risk of rejection, infections, or graft failure compared to an undetectable BK<\/jats:styled-content> level.<\/jats:p>","DOI":"10.1111\/ctr.13283","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T02:00:58Z","timestamp":1526608858000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["BK<\/scp> viremia is not associated with adverse outcomes in the absence of BK<\/scp> nephropathy"],"prefix":"10.1111","volume":"32","author":[{"given":"Amber L.","family":"Hertz\u2010Tang","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad 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