{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T04:08:13Z","timestamp":1777090093902,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T00:00:00Z","timestamp":1545782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008169","name":"Minneapolis Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008169","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>With the advent of combined antiretroviral therapy (cART), growing evidence has shown human immunodeficiency virus (HIV) may no longer be an absolute contraindication for solid organ transplantation. This study compares outcomes of heart transplantations between HIV\u2010positive and HIV\u2010negative recipients using SRTR transplant registry data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patient survival, overall graft survival and death\u2010censored graft survival were compared between HIV\u2010positive and HIV\u2010negative recipients. Multivariate Cox regression and Cox regression with a disease risk score (DRS) methodology were used to estimate the adjusted hazard ratios among heart transplant recipients (HTRs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 35 HTRs with HIV+ status were identified. No significant differences were found in patient survival (88% vs 77%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.1493), overall graft survival (85% vs 76%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.2758), and death\u2010censored graft survival (91% vs 91%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.9871) between HIV\u2010positive and HIV\u2010negative HTRs in 5\u2010year follow\u2010up. No significant differences were found after adjusting for confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study supports the use of heart transplant procedures in selected HIV\u2010positive patients. This study suggests that HIV\u2010positive status is not a contraindication for life\u2010saving heart transplant as there were no differences in graft, patient survival.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.13440","type":"journal-article","created":{"date-parts":[[2018,11,2]],"date-time":"2018-11-02T12:31:17Z","timestamp":1541161877000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Outcomes in human immunodeficiency virus\u2010infected recipients of heart transplants"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6665-0776","authenticated-orcid":false,"given":"Chao","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Outcomes and Policy University of Florida Gainesville Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuerong","family":"Wen","sequence":"additional","affiliation":[{"name":"Health Outcomes University of Rhode Island Kingston Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anju","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Nephrology Thomas Jefferson Medical School Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Belviso","sequence":"additional","affiliation":[{"name":"Health Outcomes University of Rhode Island Kingston Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Kogut","sequence":"additional","affiliation":[{"name":"Health Outcomes University of Rhode Island Kingston Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry","family":"McCauley","sequence":"additional","affiliation":[{"name":"Department of Nephrology Thomas Jefferson Medical School Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,26]]},"reference":[{"issue":"3","key":"e_1_2_7_2_1","first-page":"179","article-title":". 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