{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:35:25Z","timestamp":1760646925017,"version":"3.41.2"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T00:00:00Z","timestamp":1544054400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01DK\u201093770","K24DK090203","P30 DK 079310\u201007, 3"],"award-info":[{"award-number":["R01DK\u201093770","K24DK090203","P30 DK 079310\u201007, 3"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000102","name":"Health Resources and Services Administration","doi-asserted-by":"publisher","award":["contract 234\u20102005\u201037011C"],"award-info":[{"award-number":["contract 234\u20102005\u201037011C"]}],"id":[{"id":"10.13039\/100000102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["18CDA34110151"],"award-info":[{"award-number":["18CDA34110151"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Prior studies demonstrate poor agreement among pathologists\u2019 interpretation of kidney biopsy slides. Reliability of representative images of these slides uploaded to the United Network of Organ Sharing (UNOS) web portal for clinician review has not been studied. We hypothesized high agreement among pathologists\u2019 image interpretation, since static images eliminate variation induced by viewing different areas of movable slides. To test our hypothesis, we compared the assessments of UNOS\u2010uploaded images recorded in standardized forms by three pathologists. We selected 100 image sets, each having at least two images from kidneys of deceased donors. Weighted Cohen's kappa was used for inter\u2010rater agreement. Mean (SD) donor age was 50 (13). Acute tubular injury had kappas of 0.12, 0.14, and 0.19; arteriolar hyalinosis 0.16, 0.27, and 0.38; interstitial inflammation 0.30, 0.33, and 0.49; interstitial fibrosis 0.28, 0.32, and 0.67; arterial intimal fibrosis 0.34, 0.42, and 0.59; tubular atrophy 0.35, 0.41, and 0.52; glomeruli thrombi 0.32, 0.53, and 0.85; and global glomerulosclerosis 0.68, 0.70, and 0.77. Pathologists\u2019 agreement demonstrated kappas of 0.12 to 0.77. The lower values raise concern about the reliability of using images. Although further research is needed to understand how uploaded images are used clinically, the field may consider higher\u2010quality standards for biopsy photomicrographs.<\/jats:p>","DOI":"10.1111\/ctr.13441","type":"journal-article","created":{"date-parts":[[2018,11,2]],"date-time":"2018-11-02T13:41:18Z","timestamp":1541166078000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Reliability of deceased\u2010donor procurement kidney biopsy images uploaded in United Network for Organ Sharing"],"prefix":"10.1111","volume":"32","author":[{"given":"Sherry G.","family":"Mansour","sequence":"first","affiliation":[{"name":"Program of Applied Translational Research, Department of Medicine Yale University School of Medicine New Haven Connecticut"},{"name":"Division of Nephrology Yale University School of Medicine New Haven Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0885-8450","authenticated-orcid":false,"given":"Isaac E.","family":"Hall","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hypertension and Renal Transplantation, Department of Internal Medicine University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1440-069X","authenticated-orcid":false,"given":"Peter P.","family":"Reese","sequence":"additional","affiliation":[{"name":"Renal\u2010Electrolyte and Hypertension Division Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqi","family":"Jia","sequence":"additional","affiliation":[{"name":"Program of Applied Translational Research, Department of Medicine Yale University School of Medicine New Haven Connecticut"},{"name":"Division of Nephrology, School of Medicine Johns Hopkins University Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Thiessen\u2010Philbrook","sequence":"additional","affiliation":[{"name":"Program of Applied Translational Research, Department of Medicine Yale University School of Medicine New Haven Connecticut"},{"name":"Division of Nephrology, School of Medicine Johns Hopkins University Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilbert","family":"Moeckel","sequence":"additional","affiliation":[{"name":"Division of Pathology Yale University School of Medicine New Haven Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis L.","family":"Weng","sequence":"additional","affiliation":[{"name":"Saint Barnabas Medical Center Livingston New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica P.","family":"Revelo","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazdak A.","family":"Khalighi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anshu","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Division of Pathology Hartford Hospital Hartford Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona D.","family":"Doshi","sequence":"additional","affiliation":[{"name":"University of Michigan Ann Arbor Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Schr\u00f6ppel","sequence":"additional","affiliation":[{"name":"Section of Nephrology University Hospital Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9051-7385","authenticated-orcid":false,"given":"Chirag R.","family":"Parikh","sequence":"additional","affiliation":[{"name":"Division of Nephrology, School of Medicine Johns Hopkins University Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,6]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Organ Procurement and Transplantation Network online data reports.Secondary Organ Procurement and Transplantation Network online data reports.https:\/\/optn.transplant.hrsa.gov\/data\/view-data-reports\/national-data."},{"key":"e_1_2_7_3_1","unstructured":"United Network Organ Sharing Data Reports: Transplant Trends.Secondary United Network Organ Sharing Data Reports: Transplant 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