{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T09:30:23Z","timestamp":1772357423695,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T00:00:00Z","timestamp":1549929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["12FTF12080082"],"award-info":[{"award-number":["12FTF12080082"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR002538"],"award-info":[{"award-number":["UL1TR002538"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KL2TR002539"],"award-info":[{"award-number":["KL2TR002539"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Living donors may develop kidney dysfunction more often than equally healthy populations. The purpose of this study was to determine whether computed tomography\u2010assessed remaining kidney volume indexed to body surface area (RKV\/BSA) was associated with 1\u2010year post\u2010nephrectomy renal function independent of baseline renal function. Using multivariable regression, we modeled 1\u2010year estimated glomerular filtration rate (eGFR) and eGFR &lt;60\u00a0mL\u00a0\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup> and considered pre\u2010determined baseline eGFR subgroups in 151 consecutive donors. Mean \u00b1 SD baseline age, eGFR, RKV, BSA, and RKV\/BSA were 38\u00a0\u00b1\u00a011\u00a0years, 97\u00a0\u00b1\u00a016\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>, 153\u00a0\u00b1\u00a029\u00a0mL, 1.9\u00a0\u00b1\u00a00.2\u00a0m<jats:sup>2<\/jats:sup>, and 80.0\u00a0\u00b1\u00a012.8\u00a0ml\/m<jats:sup>2<\/jats:sup>, respectively; 50% were female and 94% were white. Mean baseline eGFR was greater with increasing RKV\/BSA tertiles (92\u00a0\u00b1\u00a014, 97\u00a0\u00b1\u00a016, 107\u00a0\u00b1\u00a016\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Post\u2010nephrectomy eGFR remained separated by RKV\/BSA tertiles. At baseline, each SD greater RKV\/BSA and eGFR was independently associated with higher adjusted 1\u2010year eGFR by 2.4 and 9.2\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>. Each SD greater age associated with 2.2\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup> lower adjusted 1\u2010year eGFR. Adjusted odds of 1\u2010year eGFR &lt;60 increased significantly for donors with RKV\/BSA &lt;80\u00a0mL\/m<jats:sup>2<\/jats:sup>. With baseline eGFR &lt;90, probability of 1\u2010year eGFR &lt;60 increased to &gt;80% with decreasing RKV\/BSA values below 80\u00a0mL\/m<jats:sup>2<\/jats:sup>. Those with baseline eGFR &gt;100 rarely developed 1\u2010year eGFR &lt;60 if RKV\/BSA remained &gt;60\u00a0mL\/m<jats:sup>2<\/jats:sup>. RKV\/BSA independently associated with 1\u2010year eGFR &lt;60, especially with lower baseline eGFRs. Additional studies should evaluate the predictive utility of this measure and its potential role in donor evaluations and informed consent.<\/jats:p>","DOI":"10.1111\/ctr.13485","type":"journal-article","created":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T22:20:50Z","timestamp":1548714050000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Baseline living\u2010donor kidney volume and function associate with 1\u2010year post\u2010nephrectomy kidney function"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0885-8450","authenticated-orcid":false,"given":"Isaac E.","family":"Hall","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Nephrology &amp; Hypertension University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akram","family":"Shaaban","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Sciences, Division of Clinical Radiology University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences, Division of Biostatistics University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena B.","family":"Sikora","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Nephrology &amp; Hypertension University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Bourija","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Sciences, Division of Clinical Radiology University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinivasan","family":"Beddhu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Nephrology &amp; Hypertension University of Utah School of Medicine Salt Lake City Utah"},{"name":"Medical Service Veterans Affairs Salt Lake City Health Care System Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuad","family":"Shihab","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Nephrology &amp; Hypertension University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12331"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12830"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03425.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfx088"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14557"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.460"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.285141"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016101084"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.04.079"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000356"},{"issue":"1","key":"e_1_2_8_12_1","first-page":"116","article-title":"Does size matter? 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