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Transplantation has become the standard of care for patients with HIV and end\u2010stage kidney or liver disease. Although less data exist for thoracic organ and pancreas transplantation, it is likely that transplantation is also safe and effective for these recipients as well. Despite what is typically a transient decline in CD4\n                    <jats:sup>+<\/jats:sup>\n                    T lymphocytes, HIV remains well controlled and infection risks are similar to those of HIV\u2010uninfected transplant recipients. The availability of effective directly active antivirals for the treatment of Hepatitis C is likely to improve outcomes in HIV and HCV co\u2010infected individuals, a population previously noted to have decreased survival. Drug interactions remain an important consideration, and integrase inhibitor\u2010based regimens are preferred due to the absence of interactions with calcineurin and mTOR inhibitors. Additionally, despite the use of more potent immunosuppression, rejection rates exceed those found in HIV\u2010uninfected recipients. Ongoing research evaluating HIV\u2010positive organ donors may provide support for utilizing these donors for HIV\u2010positive patients in need of transplantation.\n                  <\/jats:p>","DOI":"10.1111\/ctr.13499","type":"journal-article","created":{"date-parts":[[2019,2,17]],"date-time":"2019-02-17T23:46:13Z","timestamp":1550447173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":97,"title":["Solid organ transplantation in the HIV\u2010infected patient: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice"],"prefix":"10.1111","volume":"33","author":[{"given":"Emily A.","family":"Blumberg","sequence":"first","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christin 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