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Significant new developments in the field have made it necessary to divide the previous single guideline published in 2013 into two sections, with the intestinal parasites separated from this guideline devoted to tissue and blood protozoa. The current update reflects the increased focus on donor screening and risk\u2010based recipient monitoring for parasitic infections. Increased donor testing has led to new recommendations for recipient management of\n                    <jats:italic>Toxoplasma gondii<\/jats:italic>\n                    and\n                    <jats:italic>Trypanosoma cruzi<\/jats:italic>\n                    . Molecular diagnostics have impacted the field, with access to rapid diagnostic testing for malaria and polymerase chain reaction testing for\n                    <jats:italic>Leishmania<\/jats:italic>\n                    . Changes in\n                    <jats:italic>Babesia<\/jats:italic>\n                    treatment regimens in the immunocompromised host are outlined. The risk of donor transmission of free\u2010living amebae infection is reviewed. Changing immigration patterns and the expansion of transplant medicine in developing countries has contributed to the recognition of parasitic infections as an important threat to transplant outcomes. Medications such as benznidazole and miltefosine are now available to US prescribers as access to treatment of tissue and blood protozoa is increasingly prioritized.\n                  <\/jats:p>","DOI":"10.1111\/ctr.13546","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T02:29:43Z","timestamp":1553221783000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":109,"title":["Tissue and blood protozoa including toxoplasmosis, Chagas disease, leishmaniasis,\n                    <i>Babesia<\/i>\n                    ,\n                    <i>Acanthamoeba<\/i>\n                    ,\n                    <i>Balamuthia<\/i>\n                    , and\n                    <i>Naegleria<\/i>\n                    in solid organ transplant recipients\u2014 Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice"],"prefix":"10.1111","volume":"33","author":[{"given":"Ricardo M.","family":"La Hoz","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele I.","family":"Morris","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases University of Miami Miller School of Medicine Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Infectious Diseases Community of Practice of the American Society of Transplantation","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens7030065"},{"key":"e_1_2_8_3_1","unstructured":"Centers for Disease C.Parasites \u2010 Toxoplasmosis2018.https:\/\/www.cdc.gov\/parasites\/toxoplasmosis\/gen_info\/faqs.html. 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