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This updated guideline reviews the epidemiology of ventricular assist device (VAD) infections and provides recommendations for the management and prevention of these infections. Almost one half of those awaiting heart transplantation are supported with VADs. Despite advances in device technologies, VAD infections commonly complicate mechanical circulatory support and remain typified by common components and anatomic locations. These infections have important implications for transplant candidates, most notably increased wait\u2010list mortality. Strategic management of these infections is crucial for successful transplantation. Coincidentally, explantation of all VAD components at the time of transplantation is often the definitive cure for the device\u2010associated infection. Highlighted in this updated guideline is the reported success of transplantation in patients with a variety of pre\u2010existing VAD infections and guidance on post\u2010transplant management strategies.<\/jats:p>","DOI":"10.1111\/ctr.13552","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T12:33:26Z","timestamp":1553862806000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Ventricular assist device\u2010related infections and solid organ transplantation\u2014Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice"],"prefix":"10.1111","volume":"33","author":[{"given":"Christine E.","family":"Koval","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Lerner College of Medicine Case Western Reserve University Cleveland Ohio"},{"name":"Transplant Infectious Diseases, Transplant Center Cleveland Clinic Foundation Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Stosor","sequence":"additional","affiliation":[{"name":"Medicine and Surgery, Divisions of Infectious Diseases and Organ Transplantation Northwestern University Feinberg School of Medicine Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the AST ID Community of Practice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067758"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0909938"},{"key":"e_1_2_11_4_1","first-page":"357","article-title":"European results with a continuous\u2010flow ventricular assist device for advanced heart\u2010failure patients","volume":"37","author":"Lahpor J","year":"2010","journal-title":"Eur J Cardiothorac Surg"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012175"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.07.005"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.10.040"},{"key":"e_1_2_11_8_1","unstructured":"FDA.Summary of safety and effectiveness data. 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